Fifteen adenoviruses from cattle, sheep, horses, and llamas were studied by
virus neutralization to determine their degree of antigenic similarity. Prototype viruses
included bovine adenoviruses species 1-8, ovine adenoviruses species 5 and
6, and equine adenovirus species 1. Unclassified viruses that were compared to
the prototype viruses were isolated from different locations within Oregon and
were represented by bovine isolate 32CN, ovine isolates 47F and 475N, and llama
isolate 7649. Reciprocal virus neutralization tests were performed and the degree
of antigenic similarity, i.e., species differentiation was determined by criteria established
by the International Committee for the Nomenclature of Viruses.
The study showed that many of the adenoviruses, both prototype and unclassified,
shared minor antigenic components with each other. Prototype viruses possessed
major antigenic differences and, as previously demonstrated by other
investigators, should be classified as separate virus species. Bovine adenovirus
isolate 32CN was shown to be of the same species as ovine adenovirus isolate
475N, but neither isolate was similar to any of the prototype virus species studied.
Ovine adenovirus isolate 47F was shown to be of the same species as ovine adenovirus
species 5 strain RTS 42. Llama adenovirus isolate 7649, while sharing minor
antigens with different viruses from cattle and sheep, was shown to be a distinct
species. This represents the first species of adenovirus from llama. / Graduation date: 1993
| Identifer | oai:union.ndltd.org:ORGSU/oai:ir.library.oregonstate.edu:1957/36062 |
| Date | 15 March 1993 |
| Creators | Yusuf, Irwandi |
| Contributors | Mattson, Donald E. |
| Source Sets | Oregon State University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis/Dissertation |
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