High-fat diet attenuates Alzheimer's disease-related pathology and cognitive impairment in a transgenic mouse model

Description

This study investigated the effect of high-fat diet consumption on Alzheimer's disease-related pathology in the Tg6799 mouse model. We found that high-fat diet attenuates Alzheimer's disease-related pathology and cognitive dysfunction in Tg6799 mice and propose decreased beta-amyloid deposition due to improved autophagic-lysosomal flux as a potential, underlying mechanism.

Links & Downloads

1. urn:nbn:de:bsz:15-qucosa2-790692
2. https://ul.qucosa.de/id/qucosa%3A79069
3. https://ul.qucosa.de/api/qucosa%3A79069/attachment/ATT-0/

Tags

info:eu-repo/classification/ddc/610

ddc:610

Additional Fields

Identifer	oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:79069
Date	05 May 2022
Creators	Merkel, Jonathan Leonard
Contributors	Universität Leipzig
Source Sets	Hochschulschriftenserver (HSSS) der SLUB Dresden
Language	English
Detected Language	English
Type	info:eu-repo/semantics/updatedVersion, doc-type:doctoralThesis, info:eu-repo/semantics/doctoralThesis, doc-type:Text
Rights	info:eu-repo/semantics/openAccess
Relation	10.1002/trc2.12173