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Structurally optimised BODIPY derivatives for imaging of mitochondrial dysfunction in cancer and heart cells

Yes / The structural features required for mitochondrial uptake of BODIPY-based optical imaging agents have been explored. The first derivatives of this class of dyes shown to have mitochondrial membrane potential-dependent uptake in both cancer and heart cells have been developed. / Daisy Appeal Charity (Grant: DAhul0211), the University of Hull scholarship, Newcastle University, EPSRC and High Force Research Ltd, EPSRC Fellowship (EP/G005206/1)

Identiferoai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/17281
Date17 September 2019
CreatorsNigam, S., Burke, B.P., Davies, L.H., Domarkas, J., Wallis, J.F., Waddell, P.G., Waby, Jennifer S., Benoit, D.M., Seymour, A.-M., Cawthorne, C., Higham, L.J., Archibald, S.J.
Source SetsBradford Scholars
LanguageEnglish
Detected LanguageEnglish
TypeArticle, Published version
Rights(c) 2016 The Authors. This is an Open Access article distributed under the Creative Commons CC-BY license (http://creativecommons.org/licenses/by/3.0/), CC-BY

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