Psoriasis is a chronic inflammatory disease of the skin and joints associated with several
comorbidities such as arthritis, diabetes mellitus and metabolic syndrome, including
obesity, hypertension and dyslipidaemia, Crohn’s disease, uveitis and psychiatric and
psychological diseases. Psoriasis has been described as an independent risk factor for
cardiovascular diseases and thus patients with psoriasis should be monitored for the
development of cardiovascular disease or metabolic syndrome. However, there is
mounting evidence that psoriasis also affects the development of osteoporosis, an
important metabolic disease with enormous clinical and socioeconomic impact. At
present, there are still controversial opinions about the role of psoriasis in osteoporosis.
A more in depth analysis of this phenomenon is of great importance for affected patients
since, until now, bone metabolism is not routinely examined in psoriatic patients, which
might have important long-term consequences for patients and the health system. In the
present review, we summarize current knowledge on the impact of psoriatic inflammation
on bone metabolism and osteoporosis.
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:87688 |
| Date | 26 October 2023 |
| Creators | Saalbach, Anja, Kunz, Manfred |
| Publisher | Frontiers Media S.A. |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 925503 |
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