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Human memory and the medial temporal region of the brain

A clear double dissociation between the effects of left and right temporal-lobe excisions was demonstrated for two identically-designed learning tasks that utilized different memoranda. Patients with left temporal-lobe lesions showed a deficit for the verbal task and normal performance for the non-verbal analogue, whereas the converse was evident for patients with right temporal-lobe lesions. Again, on two formally similar tests of short-term recall with interpolated activity, this same pattern of dissociation was observed for the retention of verbal as compared with non-verbal information. For both pairs of experiments, the severity of the material-specific learning and retention deficits was directly related to the extent of surgical encroachment upon the hippocampal zone of the affected hemisphere. These studies implicate the hippocampal region in the crucial transfer of experience from a temporary storage system (primary memory) to more permanent long-term storage (secondary memory). / fr

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.93903
Date January 1972
CreatorsCorsi, Philip Michael
ContributorsBrenda Milner (Supervisor)
PublisherMcGill University
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Formatapplication/pdf
CoverageDoctor of Philosophy (Department of Psychology)
RightsAll items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.
Relation000947212, Theses scanned by McGill Library.

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