Thesis (M.Sc.D.)--Boston University. School of Graduate Dentistry, 1969. / Bibliography, tables included. / An investigation of the fluoride concentration of cementum of rat molars was performed utilizing sixty Sprague-Dawley rats, averaging eighty grams, thirty-one to thirty-six days of age at the onset of the project. The experimental period was from twenty-two to thirty-five days. The rats were randomly placed into seven groups and were fed Purina Laboratory chow and tap water, to which had been added either none, 50, or 100 ppm fluoride. At the conclusion of the study the first and second maxillary and mandibular molars were extracted and the apical one millimeter of each root was collected for analysis. The samples were ashed and then dissolved in l ml of 0.5 M HC10 [subscript 4] and 4 ml of 0.5 M Na Citrate. The fluoride concentration of the samples was obtained by use of the Ionalyzer (Orion Research, Inc., Mode1 401) with its component specific fluoride ion activity electrode and essential reference electrode and standardizing solutions. The results were statistically significant (p <.00l) and the mean fluoride values ranged from 500 ppm to 2,100 ppm for the controls and from 3,900 ppm to 6,500 ppm for the experimental rats ingesting 100 ppm fluoride in their drinking water. The experimental design and significance of the results are discussed.
| Identifer | oai:union.ndltd.org:bu.edu/oai:open.bu.edu:2144/29794 |
| Date | January 1969 |
| Creators | Niver, Franklin D. |
| Publisher | Boston University |
| Source Sets | Boston University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis/Dissertation |
| Rights | This work is being made available in OpenBU by permission of its author, and is available for research purposes only. All rights are reserved to the author. |
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