Healthspan describes the length of time an individual lives without
disability or chronic disease. Characteristic to aging is the risk for the onset of
both through a progressive accumulation of deficits in normal physiologic
function. In the past, the declines associated with aging were simply accepted as
inevitable. Today, longevity research has undergone a meteoric rise in popularity.
This is due to several landmark studies demonstrating that what was once thought
of as inevitable has potential to be delayed. This thesis aims to consolidate current
theories of biochemical processes believed to underlie aging, and explore their
interconnections. Furthermore, current pharmaceutical and lifestyle interventions
being studied to promote longevity and target these specific pathways will be
analyzed for safety and practicality for use in a primary care setting. Through a
shift from symptom-based care to personalized preventative care, the goal is to
maximize function into older age and empower individuals to live life to the
fullest well beyond what was previously imagined.
| Identifer | oai:union.ndltd.org:bu.edu/oai:open.bu.edu:2144/41304 |
| Date | 16 July 2020 |
| Creators | Miller, Roy |
| Contributors | Perls, Thomas, Sebastiani, Paola |
| Source Sets | Boston University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis/Dissertation |
| Rights | Attribution 4.0 International, http://creativecommons.org/licenses/by/4.0/ |
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