Asymmetric nitrene transfer reactions via metalloradical catalysis (MRC) with
azides has attracted research interest because of its fundamental and practical importance.
The resulting nitrogen-containing units are recurrent motifs in biologically important
molecules and can serve as versatile precursors in organic synthesis.
The [Co(D2-Por*)] have emerged as a new class of catalysts for asymmetric
aziridination and C-H amination. These metalloradical catalysts have been shown to be
highly effective for the asymmetric intermolecular aziridination of a broad scope of
substrates with different classes of azides with excellent to good enantioselectivity. The
intramolecular C-H amination utilizing various azides can allow for the construction of
diverse nitrogen containing heterocyclic compounds.
| Identifer | oai:union.ndltd.org:USF/oai:scholarcommons.usf.edu:etd-5787 |
| Date | 01 January 2013 |
| Creators | Tao, Jingran |
| Publisher | Scholar Commons |
| Source Sets | University of South Flordia |
| Detected Language | English |
| Type | text |
| Format | application/pdf |
| Source | Graduate Theses and Dissertations |
| Rights | default |
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