Return to search

Treatment Effect of CT-Guided Periradicular Injections in Context of Different Contrast Agent Distribution Patterns

Acutely manifesting radicular pain syndromes associated with degenerations of the lower
spine are frequent ailments with a high rate of recurrence. Part of the conservative management are
periradicular infiltrations of analgesics and steroids. The purpose of this study is to evaluate the
dependence of the clinical efficacy of CT-guided periradicular injections on the pattern of contrast
distribution and to identify the best distribution pattern that is associated with the most effective pain
relief. Using a prospective study design, 161 patients were included in this study, ensuring ethical
standards. Statistical analysis was performed, with the level of statistical significance set at p = 0.05.
A total of 37.9% of patients experienced significant but not long-lasting (four weeks on average)
complete pain relief. A total of 44.1% of patients experienced prolonged, subjectively satisfying pain
relief of more than four weeks to three months. A total of 18% of patients had complete and sustained
relief for more than six months. A significant correlation exists between circumferential, large area
contrast distribution including the zone of action between the disc and affected nerve root contrast
distribution pattern with excellent pain relief. Our results support the value of CT-guided contrast
injection for achieving a good efficacy, and, if necessary, indicative repositioning of the needle to
ensure a circumferential distribution pattern of corticosteroids for the sufficient treatment of radicular
pain in degenerative spine disease.

Identiferoai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:86001
Date13 June 2023
CreatorsReuschel, Vera, Scherlach, Cordula, Pfeifle, Christian, Krause, Matthias, Struck, Manuel Florian, Hoffmann, Karl-Titus, Schob, Stefan
PublisherMDPI
Source SetsHochschulschriftenserver (HSSS) der SLUB Dresden
LanguageEnglish
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text
Rightsinfo:eu-repo/semantics/openAccess
Relation787

Page generated in 0.0164 seconds