Submitted by SBI Biblioteca Digital (sbi.bibliotecadigital@puc-campinas.edu.br) on 2018-02-07T11:56:57Z
No. of bitstreams: 1
DEBORAH RODRIGUES PINHEIRO.pdf: 600067 bytes, checksum: 652f90a56006bb31b1c5dff817300e15 (MD5) / Made available in DSpace on 2018-02-07T11:56:57Z (GMT). No. of bitstreams: 1
DEBORAH RODRIGUES PINHEIRO.pdf: 600067 bytes, checksum: 652f90a56006bb31b1c5dff817300e15 (MD5)
Previous issue date: 2017-12-20 / Pontif?cia Universidade Cat?lica de Campinas ? PUC Campinas / Deglutition impairment is a frequent finding in the elderly, particularly in those with dementia, therefore our study?s main objective was to describe it in patients with Alzheimer's dementia (AD) and vascular dementia (VD), namely the aspects of swallowing and eating, to identify risk of dysphagia and their relation with clinical, cognitive, behavioral and neuropsychiatric symptoms. Thirty-five elderly people with a diagnosis of dementia according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, in follow-up at the Clinical Neurology Clinic of the Hospital Maternidade Celso Pierro (PUC-Campinas), participated in this study. The patients were submitted to clinical history, Mini-Mental State Examination (MMSE), Verbal Fluency Test, Neuropsychiatric Inventory (NPI), Pfeffer Functional Activities Questionnaire (PFAQ), Clinical Dementia Rating (CDR) (NPI-C) and the Speech-Language Pathology and Risk Assessment for Dysphagia (SLPRAD). 24 (68.6%) patients with AD diagnosis and 11 (31.4%) with DV were included. The mean age of the patients was 77.5 (? 9.0) years, mean formal schooling of 2.1 years and mean disease duration of 3.5 years. In the MMSE the total score was 14.2 (? 6.5) and in the verbal fluency test, the mean words were 5.6. The mean score in NPI was 18.6 (? 11.3) and in the functional evaluation (PFAQ) was 22.9. Patients were classified as mild dementia 16 (45.8%), moderate 14 (40%) and severe 5 (14.2%) cases, according to CDR. Patients with AD were significantly older than those with DV (p = 0.003). In dementia?s classification, a higher occurrence of moderate/severe dementia was observed in those with an AD when compared to those with DV (p = 0.013). In PARD, 10 (29%) patients presented normal deglutition and 25 (71%) had signs suggestive of dysphagia, 17 of those with an AD, but with no significant difference in the classification of dementia. There was no complaint of "change in appetite, weight, or eating habits" in those who presented significantly dementia classified as mild (p = 0.044). Patients who complained of coughing and coughed in the anamnesis presented significant signs suggestive of dysphagia (p = 0.007). Patients with no change in the "how to put lots of food in the mouth at once" were significantly those classified as mild (p=0.046). Comparing the subjects' ages with the oral and pharyngeal phases of PARD, it was observed that those who presented alterations in the oral phase (p = 0.024) and in the pharyngeal phase (p = 0.03) were significantly older when compared to those who did not present changes. In relation to MMSE, when compared to those without pharyngeal changes, they presented a significantly worse performance in calculus (p = 0.020) and language (p = 0.031). Patients with suggestive signs of dysphagia had a significant change in Oral Phase and Pharyngeal Phase (p = 0.000) when compared to those without signs suggestive of dysphagia. Those with "change in appetite, weight or eating habits" in the NPI-C had a significant change in the Pharyngeal Phase (p = 0.035) of PARD when compared to those without changes. The incidence of change in appetite, weight or eating habits was high, and the severity of dementia was significantly related. The presence of choking or coughing was observed in 25% of cases, and occurred at all ages. Signs suggestive of dysphagia were elevated in PARD in our sample, but there was no relation with the behavioural and neuropsychiatric aspects. The clinical complaint of gagging and cough was significantly correlated with signs suggestive of dysphagia. Alterations in the oral and pharyngeal phase of PARD occurred significantly in older subjects. Cognitive alterations were associated with alteration in the pharyngeal PARD?s deglutition. / O comprometimento da degluti??o ? um achado frequente em idosos particularmente naqueles com quadros de dem?ncia, assim o objetivo do nosso trabalho foi descrever em pacientes com dem?ncia de Alzheimer (DA) e dem?ncia vascular (DV), aspectos da degluti??o e da alimenta??o, identificar risco de disfagia e suas rela??es com aspectos cl?nicos, cognitivos, comportamentais e sintomas neuropsiqui?tricos. Participaram deste estudo 35 idosos com diagn?stico de dem?ncia segundo os crit?rios do Manual Diagn?stico e Estat?stico dos Transtornos Mentais, em acompanhamento no Ambulat?rio de Neurologia Cl?nica do Hospital Maternidade Celso Pierro (PUC-Campinas). Os pacientes foram submetidos a: hist?ria cl?nica, Mini-Exame do Estado Mental (MEEM), teste de Flu?ncia Verbal, Invent?rio Neuropsiqui?trico (INP), Question?rio de Atividades Funcionais de Pfeffer (QAFP), Clinical Dementia Rating (CDR), question?rio para avalia??o de dist?rbio do apetite e da alimenta??o (NPI-C) e pelo Protocolo Fonoaudiol?gico de Avalia??o do Risco para Disfagia (PARD). Foram inclu?dos 24 (68,6%) pacientes com diagn?stico de DA e 11 (31,4%) com DV. A idade m?dia dos pacientes foi de 77,5 (?9,0) anos, escolaridade m?dia formal de 2,1 anos e tempo m?dio de doen?a de 3,5 anos. No MEEM o escore total foi de 14,2 (?6,5) e no teste de flu?ncia verbal, a m?dia de palavras foi de 5,6. O escore m?dio no INP foi 18,6 (?11,3) e na avalia??o funcional (QAFP) foi de 22,9. Os pacientes foram classificados em dem?ncia leve 16 (45,8%), moderada 14 (40%) e grave 5 (14,2%) casos, conforme o CDR. Os pacientes com DA eram, de modo significativo, mais velhos que aqueles com DV (p=0.003). Na classifica??o da dem?ncia foi observada maior ocorr?ncia de moderado/grave naqueles com DA quando comparados aos com DV (p=0.013). No PARD, 10 (29%) pacientes apresentaram degluti??o normal e 25 (71%) apresentaram sinais sugestivos de para disfagia, desse n?mero 17 casos com DA, mas sem diferen?a significativa na classifica??o da dem?ncia. N?o houve queixa de ?mudan?a no apetite, no peso ou nos h?bitos alimentares? nos que apresentaram de modo significativo dem?ncia classificada como leve (p=0,044). Os pacientes que apresentaram queixa de engasgos e tosse, na anamnese apresentam de modo significativo sinais sugestivos para disfagia (p=0,007). Os pacientes sem altera??o na quest?o ?como colocar muita comida na boca de uma vez s??, eram de modo significativo aqueles classificados como leve (p=0,046). Comparando a idade dos sujeitos com as fases oral e far?ngea do PARD foi observado que aqueles que apresentaram altera??o na fase oral (p=0,024) e na fase far?ngea (p=0,03) eram de modo significativo mais velhos quando comparados aos que n?o apresentaram altera??es. Em rela??o ao MEEM quando comparados aos sem altera??es na fase far?ngea apresentaram de modo significativo pior desempenho em c?lculo (p=0,020) e em linguagem (p=0,031). Os pacientes com sinais sugestivos para disfagia apresentaram de modo significativo altera??o na Fase Oral e na Fase Far?ngea (p=0,000), quando comparados aos sem sinais sugestivos para disfagia. Aqueles com ?mudan?a no apetite, no peso ou nos h?bitos alimentares? no NPI-C apresentaram de modo significativo altera??o na Fase Far?ngea (p=0,035) do PARD, quando comparados aos sem mudan?as. Foi elevada a queixa de mudan?a no apetite, no peso ou nos h?bitos alimentares, e era relacionada de modo significativo a gravidade da dem?ncia. A presen?a de queixa de engasgo ou tosse foi observada em 25% casos, e ocorreu em todas as idades. Foi elevada a ocorr?ncia de sinais sugestivos para disfagia, no PARD, na nossa amostra, mas n?o houve rela??o com os aspectos comportamentais e neuropsiqui?tricos. A queixa cl?nica de engasgos e tosse correlacionou-se de modo significativo com sinais sugestivos para disfagia. Altera??es na fase oral e far?ngea, do PARD ocorreram de modo significativo nos sujeitos mais velhos. Altera??es cognitivas associaram-se a altera??o na degluti??o na far?ngea do PARD.
| Identifer | oai:union.ndltd.org:IBICT/oai:tede.bibliotecadigital.puc-campinas.edu.br:tede/1003 |
| Date | 20 December 2017 |
| Creators | Pinheiro, Deborah Rodrigues |
| Contributors | Tedrus, Gloria Maria de Almeida Souza, Luchesi, Karen Fontes, Oliveira, I?ra Bittante de |
| Publisher | Pontif?cia Universidade Cat?lica de Campinas, Programa de P?s-Gradua??o em Ci?ncias da Sa?de, PUC-Campinas, Brasil, CCV ? Centro de Ci?ncias da Vida |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Format | application/pdf |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da PUC_CAMPINAS, instname:Pontifícia Universidade Católica de Campinas, instacron:PUC_CAMP |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 6411916762624721206, 500, 500, 600, -8538742193007695607, 6947100024386004490 |
Page generated in 0.003 seconds