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Previous issue date: 2008-08-28 / The goal of this study was to evaluate the prevalence of specific IgG antibodies against PB19
virus, which identify previous immunity, and IgM antibodies, characteristic of acute infection,
in women of childbearing age in Goiânia, a capital city in the Midwestern Region of Brazil. To
achieve this, 101 serum samples collected from health women identified via prenatal care
services, birth control groups, communitarian work groups, and public night schools near
Public Health Units were tested. The samples were stored in the section of Parasitology of the
Tropical Pathology and Public Health Institute of the Federal University of Goiás (IPTSP/UFG)
and were tested using ELISA (IgM and IgG) against parvovirus B19. The women were
evaluated according to several aspects (economic, social, cultural, age, marital status,
previous blood transfusion, pregnancy evolution, among others). The statistical tests used
were variance analysis,
2
, and multivariance analysis (logistic regression). The results
showed that the population analyzed was young, poor, presented low level of formal
education, underwent regular prenatal care exams (in terms of number of attendances), and
lived in brick houses with few rooms and many inhabitants, with a regular sanitation system.
Prevalence of previous PB19 infection was the lowest found in the literature available (8.9%),
average prevalence detected was 60%, and acute infection was 26.7%, similar to the one
found in periods of epidemics. Furthermore, 25% of the acutely infected women were
pregnant during the sample collection, which represented a risk of vertical transmission. / Objetivou-se avaliar a prevalência de anticorpos específicos das classes IgG contra o vírus
PB19, identificadores de imunidade prévia, e IgM, característicos de infecção aguda, em
mulheres em idade fértil no município de Goiânia. Para isso, foram testados 101 soros
coletados em mulheres saudáveis atendidas nos serviços de atendimento pré-natal, controle
de natalidade, grupos comunitários e escolas noturnas próximo às Unidades Públicas de
Saúde. Os soros estavam armazenados no setor de Parasitologia do Instituto de Patologia
Tropical e Saúde Pública da Universidade Federal de Goiás (IPTSP/UFG) e foram testados por
ELISA (IgM e IgG) contra o parvovírus B19. As mulheres foram avaliadas sob vários aspectos
(econômico, social, cultural, idade, estado conjugal, história de transfusão sanguínea,
evolução da gravidez, entre outros). Os testes estatísticos usados foram análise de variância,
2 e análise multivariada (regressão logística). Os resultados mostraram tratar-se de
população jovem, carente, com baixo nível de escolaridade, saneamento básico regular, pré-
natal regular (em quantidade de consultas), morando em casas de tijolo, porém com poucos
cômodos e muitos habitantes. A prevalência da infecção prévia pelo PB19 foi a mais baixa da
literatura (8,9%), sendo a prevalência média descrita de 60% e a de infecção aguda de
26,7%, semelhante à encontrada nos períodos epidêmicos. Além do mais, 25% das mulheres
agudamente infectadas estavam grávidas no período de coleta, o que representou risco de
transmissão vertical.
| Identifer | oai:union.ndltd.org:IBICT/oai:repositorio.bc.ufg.br:tede/6382 |
| Date | 28 August 2008 |
| Creators | Rios, Washington Luiz Ferreira |
| Contributors | Avelino, Mariza Martins, Castro, Ana Maria de, Avelino, Mariza Martins, Souza, Juarez Antônio de, Almeida Netto, Joaquim Caetano de |
| Publisher | Universidade Federal de Goiás, Programa de Pós-graduação em Medicina Tropical e Saúde Publica (IPTSP), UFG, Brasil, Instituto de Patologia Tropical e Saúde Pública - IPTSP (RG) |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | Portuguese |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Format | application/pdf |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da UFG, instname:Universidade Federal de Goiás, instacron:UFG |
| Rights | http://creativecommons.org/licenses/by-nc-nd/4.0/, info:eu-repo/semantics/openAccess |
| Relation | 6085308344741430434, 600, 600, 600, -7769011444564556288, 1767748423488408711 |
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