Brain can be considered as a porous medium. The brain cells form a solid phase while the liquid-filled
extracellular space (ECS) forms a porous phase that surrounds each individual cell. Brain ECS is of a
fundamental importance for brain function [1]. It serves as a reservoir for ions and a channel for
diffusion-mediated transport of biologically significant molecules and therapeutics. ECS volume is the
main factor governing the extracellular concentrations of these substances. Any ECS volume change
may lead to a change in concentration of ions and transported substances, and this has consequences for
brain function.
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:38258 |
| Date | 06 February 2020 |
| Creators | Hrabetova, S., Hrabe, J. |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/acceptedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 19, urn:nbn:de:bsz:15-qucosa2-378382, qucosa:37838 |
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