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Construction and screening of a DNA library to detect integrated hepatitis B virus DNA

Degree awarded with distinction on 6 December l995.
A dissertation submitted to the Faculty of Science, University the Witwatersrand,
in fulfilment of the requirements for the degree of Master of Science.
March. 1995 / Hepatitis B virus (HBV) infection resulting in integration of the viral DNA into host
liver cell DNA is associated with the development of hepatocellular carcinoma
(HCC). This is indicated by epidemiological trends, molecular studies and studies of
animal models infected with viruses closely related to HBv. However, little is
known about the mechanism by which the integrated HBV DNA includes HCC
despite continuing analysis of the integrated HBV DNA and its surrounding cellular
sequences. [Abbreviated Abstract. Open document to view full version]

Identiferoai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:wits/oai:wiredspace.wits.ac.za:10539/20873
Date16 August 2016
CreatorsBondonno, Catherine Patricia
Source SetsSouth African National ETD Portal
LanguageEnglish
Detected LanguageEnglish
TypeThesis
Formatapplication/pdf

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