Optofluidics is a relatively new and exciting field that includes the integration of optical waveguides into microfluidic platforms. The purpose of this field of study is to miniaturize previously developed optical systems used for biological and chemical analysis with the end goal of placing bench-top optics into microscopic packages. Mundane optical alignment and sample manipulation procedures would then be intrinsic to the platform and allow measurements to be completed quickly and with reduced human interaction. Biosensors based on AntiResonant Reflecting Optical Waveguides (ARROWs) consist of hollow-core waveguides used for fluid sample manipulation and analysis, as well as solid-core waveguides used in interfacing external components located at the chip edges. Hollow-core ARROWs are particularly useful for their ability to provide specifically tailored analyte volumes that are easily configurable depending upon the target experiment. Adaptations of standard planar microfabrication methods allow for complex integrated ARROW designs. Integrated spectral filtering with high rejection can be implemented on-chip, removing the need for additional off-chip components and increasing device sensitivity. Additional techniques to increase device sensitivity and utility, such as hybrid ARROW platforms and optical manipulation of samples, are also explored.
| Identifer | oai:union.ndltd.org:BGMYU2/oai:scholarsarchive.byu.edu:etd-4074 |
| Date | 09 August 2011 |
| Creators | Phillips, Brian S. |
| Publisher | BYU ScholarsArchive |
| Source Sets | Brigham Young University |
| Detected Language | English |
| Type | text |
| Format | application/pdf |
| Source | Theses and Dissertations |
| Rights | http://lib.byu.edu/about/copyright/ |
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