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Perfil lip?dico de pacientes com s?ndrome coronariana aguda sem supradesnivelamento de ST

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Previous issue date: 2012-03-29 / Objective: Analyze the lipid profile of patients with SCASSST/Unstable Angina and IAM with no ST-segment elevation (IAMSSST), including the determination of non- HDL-C. Methods: Observational Transversal. Study analyzed data of 1080 admitted patients with Acute Coronary Syndrome (IA/IAMSSST at the cardiovascular Intensive care unit at PUCRS-S?o Lucas Hospital between the period of September/1999 and October/2010. Analysis of the lipid profile were realized in the first 24h of the admission. Results: Among the 1080 patients, 51,9% male, 32,9% diabetics, 84,1% presented systemic arterial hypertension,26,1 smokers. In the analyzed sample it was observed that 53,4% of the patients had been using hypolipidemic treatment. At the lipid profile it was observed that 44,8% of patients presented abnormal levels of Triglycerides, 66,6% (men) and 73,3 (women) HDL-C out of goals; 30,2% of patients presented total cholesterol >200mg/dL, and 24,4% had LDL-C >130mg/dl and 51,7% LDL-C >100mg/dL. Among the 1080 patients 182 had triglycerides >200mg/dL associated to LDL-C > 130mg/dL of which, 58 patients (31,9%) presented non-HDL-C >160mg/dL. Conclusion: The results of our study demonstrate that the majority of patients with SCA (AI/IAMSSST) had low HDL-C and about half of them presented LDL-C <100mg/dL. The non-HDL-C had been elevated in one third of the patients, associated to elevated triglycerides levels / Introdu??o: A dislipidemia ? um dos principais fatores de risco para a doen?a arterial coronariana, por?m cerca de um ter?o dos pacientes com infarto agudo do mioc?rdio est?o com n?veis de colesterol total e LDL-C normais. H? poucos dados do perfil lip?dico e do n?o-HDL-colesterol (n?o-HDL-C), em pacientes com s?ndrome coronariana aguda sem supradesnivelamento de ST (SCASSST). Objetivo: Analisar o perfil lip?dico de pacientes com SCASSST/Angina Inst?vel e IAM sem supradesnivelamento de ST (IAMSSST), incluindo-se a determina??o do n?o-HDL-C. M?todos: Estudo observacional transversal analisou 1080 pacientes internados com S?ndrome Coronariana Aguda (AI/IAMSSST) na Unidade de Terapia Intensiva Cardiovascular do Hospital S?o Lucas-PUCRS, entre setembro/1999 a outubro/2010. Foram realizadas an?lises do perfil lip?dico nas primeiras 24h da admiss?o. Resultados: Entre os 1080 pacientes, 51,9% do sexo masculino, 32,9% diab?ticos, 84,1% apresentavam hipertens?o arterial sist?mica e 26,1% tabagistas. Na amostra analisada, observou-se que 53,4% dos pacientes faziam o uso de tratamento hipolipemiante. Na an?lise do perfil lip?dico observou-se: 44,8% apresentaram n?veis de triglicer?deos anormais; 66,6% (homens) e 73,3% (mulheres) HDL-C fora das metas; 30,2% dos pacientes apresentavam colesterol total >200mg/dL, sendo que 24,4% tinham LDL-C >130mg/dL e 51,7% LDL-C >100mg/dL. Entre os 1080 pacientes, 182 tinham triglicer?deos >200mg/dL associado a LDL-C > 130mg/dL; destes, 58 pacientes (31,9%) apresentavam n?o-HDL-C >160mg/dL. Conclus?o: Os resultados do nosso estudo demonstram que a maioria dos pacientes com SCA (AI/IAMSSST) tinham HDL-C baixo e cerca de metade apresentavam LDL-C <100mg/dL. O n?o-HDL-C esteve elevado em um ter?o dos pacientes associado a n?veis elevados de triglicer?deos.

Identiferoai:union.ndltd.org:IBICT/oai:tede2.pucrs.br:tede/1690
Date29 March 2012
CreatorsBervian, Juliana
ContributorsBodanese, Luiz Carlos
PublisherPontif?cia Universidade Cat?lica do Rio Grande do Sul, Programa de P?s-Gradua??o em Medicina e Ci?ncias da Sa?de, PUCRS, BR, Faculdade de Medicina
Source SetsIBICT Brazilian ETDs
LanguagePortuguese
Detected LanguagePortuguese
Typeinfo:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis
Formatapplication/pdf
Sourcereponame:Biblioteca Digital de Teses e Dissertações da PUC_RS, instname:Pontifícia Universidade Católica do Rio Grande do Sul, instacron:PUC_RS
Rightsinfo:eu-repo/semantics/openAccess
Relation7620745074616285884, 500, 600, -8624664729441623247

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