Return to search

mRNA Cap Methylation in Pluripotency and Differentiation

Yes / The mRNA cap stabilizes transcripts and
recruits processing and translation
factors. Grasso et al. report that the
mRNA cap methyltransferase RNMTRAM
is highly expressed in embryonic
stem cells and is important for
pluripotency-associated gene
expression. Repression of RAM occurs
during neural differentiation and is
important for expression of neuralassociated
genes. / Wellcome Trust

Identiferoai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/8769
Date02 August 2016
CreatorsGrasso, L., Suska, O., Davidson, L., Gonatopolous-Pournatzis, T., Williamson, Ritchie, Wasmus, L., Wiedlich, S., Peggie, M., Stavridis, M.P., Cowling, V.H.
Source SetsBradford Scholars
LanguageEnglish
Detected LanguageEnglish
TypeArticle, Published version
Rights(c) 2016 The Authors. This is an Open Access article under the CC-BY license (http://creativecommons.org/licenses/by/4.0/ ), CC-BY

Page generated in 0.0016 seconds