Yes / Background: Soft contact lenses have been developed and licensed for reducing myopia progression. These lenses
have different designs, such as extended depth of focus (EDOF) and dual focus (DF). In this prospective, doublemasked, cross-over study, different lens designs were investigated to see whether these had impact on accommodative microfluctuations and eye movements during reading.
Methods: Participants were fitted with three lenses in a randomised order; a single vision (SV) design (Omafilcon
A2; Proclear), a DF design (Omafilcon A2; MiSight), and an EDOF lens design (Etafilcon A; NaturalVue),.
Accommodative microfluctuations were measured at 25 cm for at least 60s in each lens, using a Shin-Nippon
SRW-5000 autorefractor adapted to continuously record accommodation at 22Hz. Eye movement data was
collected with the Thomson Clinical Eye Tracker incorporating a Tobii Eye bar. Eye movements include fixations
per row, fixations per minute, mean regressions per row, total number of regressions, and total rightward saccades. Accommodation data was analysed using power spectrum analysis. Differences between the lenses were
compared using a related sample two-way Friedman test.
Results: Twenty-three participants (18–29 years) were recruited to take part. The average mean spherical error
was − 2.65D ± 1.42DS, with an average age of 23.4 ± 3.5 years. No significant difference for accommodative
microfluctuations was found. Significant differences were found for fixations per row (P = 0.03), fixations per
minute (P = 0.008), mean regressions per row (P = 0.002), and total number of regressions (P = 0.002), but not
total rightward saccades (P = 0.10). Post-hoc analysis indicated the EDOF lens results were significantly different
from the other lenses, with more regressive eye movements observed.
Conclusions: Regressive saccades appear to increase when wearing EDOF lens designs, which may impact visual
comfort. Further studies in children, over a longer period of adaptation are necessary to assess the potential
impact of this finding on daily reading activities in children. / This project was supported by the British Contact Lens Association Summer Studentship Award (recipient Muskaan Hussain).
| Identifer | oai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/19735 |
| Date | 15 December 2023 |
| Creators | Ghorbani Mojarrad, Neema, Hussain, M., Mankowska, Aleksandra, Mallen, Edward A.H., Cufflin, Matthew P. |
| Source Sets | Bradford Scholars |
| Language | English |
| Detected Language | English |
| Type | Article, Published version |
| Rights | © 2023 The Authors. Published by Elsevier Ltd on behalf of British Contact Lens Association. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)., CC-BY |
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