Return to search

Model-based Comparison of Cell Density-dependent Cell Migration Strategies

Here, we investigate different cell density-dependent migration strategies. In particular, we consider strategies which differ in the precise regulation of transitions between resting and motile phenotypes. We develop a lattice-gas cellular automaton (LGCA) model for each migration strategy. Using a mean-field approximation we quantify the corresponding spreading dynamics at the cell population level. Our results allow for the prediction of cell population spreading based on experimentally accessible single cell migration parameters.

Identiferoai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:39048
Date17 April 2020
CreatorsHatzikirou, H., Böttger, K., Deutsch, A.
PublisherCambridge University Press
Source SetsHochschulschriftenserver (HSSS) der SLUB Dresden
LanguageEnglish
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text
Rightsinfo:eu-repo/semantics/openAccess
Relation0973-5348, 1760-6101, 10.1051/mmnp/201510105, info:eu-repo/grantAgreement/Deutsche Forschungsgemeinschaft/Excellence “Center for Advancing Electronics Dresden”/EXC1056/

Page generated in 0.0025 seconds