This dissertation examines the relation between occupational exposure to the solvent
methylene chloride and mortality in a cohort of cellulose fiber production workers. The
first paper, entitled The Mortality of Cellulose Fiber Production Workers, presents the main
results of the mortality follow-up of the cellulose fiber workers cohort through
September 1, 1986. Mortality from neoplastic and non-neoplastic disease among
cellulose fiber production workers is compared to that of the U.S. and local (county
level) populations, while controlling for the effects of gender, race, calendar period, and
age. Mortality from cancers of the lung, breast, and pancreas, and ischemic heart disease
was less than expected. Excess mortality was observed for melanoma of the skin, cancer
of the buccal cavity and pharynx, tumors of the liver and biliary tract, and accidental
deaths. Three deaths from cancer of the bile ducts were observed (3 observed, 0.15
expected, SMR=20). This is the first known report of an association between exposure
to methylene chloride and cancer of the bile ducts. [TRUNCATED]
| Identifer | oai:union.ndltd.org:bu.edu/oai:open.bu.edu:2144/20801 |
| Date | January 1991 |
| Creators | Cohen, Aaron J. |
| Publisher | Boston University |
| Source Sets | Boston University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis/Dissertation |
| Rights | This dissertation is being made available in OpenBU by permission of its author, and is available for research purposes only. All rights are reserved to the author. |
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