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Studies on the effect of alterations in airway CO2 tension on respiratory mechanical work and airway resistance.

Since Liljestrand's classic work on the O2 cost of ventilation (10) there has been ample confirmation of his finding that voluntary hyperventilation requires more oxygen per litre ventilated than if hyperventilation is CO2 driven at the same frequency and tidal volume (1,6,7,10,13,17,18). Figure 1 illustrates this point graphical1y and shows two families of curves. One (solid lines), representing the oxygen cost of carbon dioxide driven hyperventilation while the other (dotted lines) represents the considerably greater oxygen cost of voluntary hyperventilation at any chosen minute ventilation. Liljestrand's explanation that the greater O2 cost of voluntary hyperventilation was due to the less efficient use of the respiratory muscles during voluntary as compared with CO2 driven hyperventilation has been generally accepted by most investigators. [...]

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.116594
Date January 1964
CreatorsNewhouse, Michael T.
ContributorsMcGregor, M. (Supervisor)
PublisherMcGill University
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Formatapplication/pdf
CoverageMaster of Science. (Department of Experimental Medicine. )
RightsAll items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.
Relationalephsysno: NNNNNNNNN, Theses scanned by McGill Library.

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