by Maria Wan-Yin Lau Wong. / Thesis (M.Phil.)--Chinese University of Hong Kong, 1990. / Bibliography: leaves 121-133. / SUMMARY --- p.1 / INTRODUCTION --- p.3 / Chapter CHAPTER 1 --- IRON METABOLISM --- p.7 / Chapter 1.1 --- EXCRETION --- p.7 / Chapter 1.2 --- ABSORPTION --- p.8 / Chapter 1.3 --- IRON TRANSPORT AND STORAGE --- p.11 / Chapter 1.3.1 --- TRANSFERRIN --- p.11 / Chapter 1.3.2 --- STORAGE --- p.14 / Chapter CHAPTER 2 --- DISEASES ASSOCIATED WITH IRON DEFICIENCY OR OVERLOAD --- p.16 / Chapter 2.1 --- IRON DEFICIENCY ANEMIAS --- p.16 / Chapter 2.1.1 --- NUTRITIONAL DEFICIENCY --- p.17 / Chapter 2.1.2 --- IMPAIRED ABSORPTION --- p.17 / Chapter 2.1.3 --- INCREASED IRON REQUIREMENTS --- p.18 / Chapter 2.1.4 --- INCREASED IRON LOSS --- p.19 / Chapter 2.2 --- IRON OVERLOAD --- p.20 / Chapter 2.2.1 --- INCREASED IRON ABSORPTION --- p.21 / Chapter 2.2.2 --- PARENTERAL IRON OVERLOAD --- p.25 / Chapter 2.2.3 --- FOCAL IRON DEPOSITION --- p.26 / Chapter 2.2.4 --- NEONATAL HEMOCHROMATOSIS --- p.27 / Chapter 2.2.5 --- IRON STATUS IN HONG KONG POPULATION --- p.28 / Chapter 2.2.6 --- PREVALENCE OF IRON OVERLOAD IN VARIOUS REGIONS --- p.28 / Chapter 2.3 --- IRON STORAGE DISEASE --- p.29 / Chapter CHAPTER 3 --- ASSESSMENT OF IRON OVERLOAD --- p.31 / Chapter 3.1 --- SERUM PARAMETER --- p.31 / Chapter 3.1.1 --- SERUM IRON --- p.31 / Chapter 3.1.2 --- TRANSFERRIN SATURATION --- p.31 / Chapter 3.1.3 --- SERUM FERRITIN --- p.32 / Chapter 3.2 --- NON-SERUM PARAMETER --- p.34 / Chapter 3.2.1 --- HLA TYPING --- p.34 / Chapter 3.2.2 --- HEPATIC IRON CONCENTRATION --- p.35 / Chapter 3.2.3 --- HISTOLOGICAL ASSESSMENT --- p.35 / Chapter 3.2.3(i) --- HEPATIC MORPHOLOGY --- p.36 / Chapter 3.2.4 --- NON-INVASIVE PROCEDURE --- p.38 / Chapter CHAPTER 4 --- MATERIALS AND METHODS --- p.39 / Chapter METHOD 1: --- HAEMATOXYLIN AND EOSIN STAIN --- p.43 / Chapter METHOD 2: --- PERLS' PRUSSIAN BLUE --- p.44 / Chapter METHOD 3: --- ROWE'S HISTOLOGICAL GRADING SYSTEM OF IRON DEPOSITION --- p.45 / Chapter METHOD 4: --- SEARLE'S IRON GRADING SYSTEM --- p.47 / Chapter METHOD 5: --- PARAFFIN REMOVAL --- p.48 / Chapter METHOD 6: --- CHEMICAL DETERMINATION OF IRON CONCENTRATION BY ATOMIC ABSORPTION SPECTROPHOTOMETRY --- p.49 / Chapter CHAPTER 5 --- RESULTS --- p.50 / Chapter 5.1 --- CHEMICAL DETERMINATION --- p.50 / Chapter 5.2 --- CONTROL GROUP --- p.53 / Chapter 5.3 --- HISTOLOGICAL STUDY --- p.54 / Chapter 5.3.1 --- NEONATES AND INFANTS --- p.55 / Chapter 5.3.2 --- CHILDREN AND ADOLESCENCE --- p.56 / Chapter 5.3.3 --- ADULT IRON STORAGE --- p.56 / Chapter 5.4 --- SEX DISTRIBUTION --- p.57 / Chapter 5.5 --- AGE DISTRIBUTION --- p.58 / Chapter 5.6 --- ASSOCIATION BETWEEN SIDEROSIS IN HEPATOCYTES AND KUPFFER CELLS --- p.58 / Chapter 5.7 --- ASSOCIATION OF HEPATOCYTIC IRON WITH FIBROSIS --- p.59 / Chapter 5.8 --- SYSTEMIC TISSUES --- p.59 / Chapter 5. 11 --- HEPATOCYTIC IRON DETERMINED BY SEARLE'S METHOD --- p.61 / TABLES AND FIGURES --- p.63 / Chapter CHAPTER 6 --- DISCUSSION --- p.102 / Chapter 6.1 --- CORRELATION BETWEEN HISTOLOGICAL AND CHEMICAL DETERMINATION OF IRON IN THE LIVER --- p.102 / Chapter 6.2 --- IRON CONTENT OF NEONATES --- p.105 / Chapter 6.3 --- IRON CONTENT OF THE ADOLESCENCE AND CHILDREN GROUP --- p.106 / Chapter 6.4 --- IRON CONTENT OF THE ADULT GROUP --- p.106 / Chapter 6.5 --- RELATIONSHIP OF SIGNIFICANT IRON DEPOSITION WITH SEX --- p.108 / Chapter 6.6 --- ASSOCIATION OF SIFNIFICANT IRON DEPOSITION WITH AGE --- p.108 / Chapter 6.7 --- MODE OF IRON DISTRIBUTION IN THE LIVER --- p.109 / Chapter 6.8 --- ASSOCIATION WITH FIBROSIS --- p.111 / Chapter 6.9 --- RELATIONSHIP WITH SYSTEMIC TISSUES --- p.112 / Chapter 6.10 --- THE CONTROL GROUP --- p.114 / Chapter 6.11 --- SEARLE'S IRON GRADING --- p.115 / Chapter 6.12 --- SIDEROSIS IN THE HONG KONG POPULATION --- p.116 / Chapter CHAPTER 7 --- CONCLUSION --- p.119 / REFERENCES --- p.121
| Identifer | oai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_318572 |
| Date | January 1990 |
| Contributors | Chinese University of Hong Kong Graduate School. Division of Clinical and Pathological Sciences. |
| Publisher | Chinese University of Hong Kong |
| Source Sets | The Chinese University of Hong Kong |
| Language | English |
| Detected Language | English |
| Type | Text, bibliography |
| Format | print, 133 leaves : ill. (some col.) ; 30 cm. |
| Coverage | Hong Kong |
| Rights | Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
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