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Associations Between Cocaine, Amphetamine or Psychedelic Use and Psychotic Symptoms in a Community Sample

Objective: To investigate whether there is an association between use of cocaine, amphetamines, or psychedelics and psychotic symptoms.

Method: Cumulated data from a prospective, longitudinal community study of 2588 adolescents and young adults in Munich, Germany were used. Substance use was assessed at baseline, 4-year and 10-year follow-up using the Munich Composite International Diagnostic Interview; psychotic symptoms were assessed at 4-year and 10-year follow-up. Multinomial logistic regression analyses, adjusted for sociodemographic factors, common mental disorders, other substance use, and childhood adversity (adjusted odds ratios, AOR), revealed associations between cocaine, amphetamine or psychedelic use and psychotic symptoms.

Results: Lifetime experience of psychotic symptoms was associated with lifetime use of cocaine (AOR 1.94; 95%CI 1.10-3.45), amphetamines (AOR 1.69; 95%CI 0.98-2.93), psychedelics (AOR 2.37; 95%CI 1.20-4.66) and all three substances (AOR 1.95; 95%CI 1.19-3.18).

Conclusion: Associations between psychotic symptoms and use of cocaine, amphetamines, and/or psychedelics in adolescents and young adults call for further studies to elucidate risk factors and developmental pathways.

Identiferoai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:27049
Date January 2011
CreatorsKuzenko, Nina, Sareen, Jitender, Beesdo-Baum, Katja, Perkonigg, Axel, Höfler, Michael, Simm, James, Lieb, Roselind, Wittchen, Hans-Ulrich
PublisherTechnische Universität Dresden
Source SetsHochschulschriftenserver (HSSS) der SLUB Dresden
LanguageEnglish
Detected LanguageEnglish
Typedoc-type:article, info:eu-repo/semantics/article, doc-type:Text
SourceActa Psychiatrica Scandinavica, Bd. 123 (2011), Nr. 6, S. 466–474, ISSN: 0001-690X
Rightsinfo:eu-repo/semantics/openAccess
Relation10.1111/j.1600-0447.2010.01633.x

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