The World Health Organization (WHO) estimates that one billion people worldwide suffer from central
nervous system (CNS) disorders [1]. One major issue in treating these disorders is inadequate drug
penetration which can be attributed to an effective blood-brain-barrier that limits passage across blood
vessels. Low diffusivity of large classes of drug compounds restricts transport across blood vessel walls
and subsequent passage through surrounding brain tissues. Tissue transport is emerging as an
increasingly important area of research in drug delivery since the vast majority of therapeutic agents
must traverse this space before reaching their targets.
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:38050 |
| Date | 30 January 2020 |
| Creators | Sarntinoranont, Malisa, Mareci, Thomas H. |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/acceptedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 6, urn:nbn:de:bsz:15-qucosa2-378382, qucosa:37838 |
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