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Bisphosphonate-loaded hydroxyapatite-coated implant surfaces : physico-chemical characterisation and bone cell culture studies

This thesis investigates bisphosphonate adsorption onto plasma sprayed HA (PS-HA) and simulated body fluid-grown HA (SBF-HA) coatings commonly used for orthopaedic implants. Bisphosphonates exhibit high binding affinity for the calcium present in HA and hence can be adsorbed onto HA-coated implants to exploit their beneficial properties for improved bone growth at the implant interface.

Identiferoai:union.ndltd.org:ADTP/202021
Date January 2007
CreatorsMcLeod, Kate
Source SetsAustraliasian Digital Theses Program
LanguageEN-AUS
Detected LanguageEnglish
RightsCopyright Kate McLeod 2007

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