Xanthogranulomatosis is a common dermatological disease in birds. This form of inflammation, possibly associated with lipometabolic disorders, can also be seen in visceral organs, which
as yet has only rarely been described in avian medicine. In general, diseases related to impaired
lipid metabolism are frequently reported in avian medicine, with hepatic steatosis and atherosclerosis being the most common. In human medicine, infectious agents—especially some strains of
adenovirus—were implicated in contributing to lipometabolic disorders; this has also been described
for chicken. Here, a case series of six Red-crowned Parakeets (Cyanoramphus novaezelandiae) is presented, all cases being characterized by psittacine adenovirus 2 (PsAdV-2) infection with or without
disseminated xanthogranulomatosis. The affected individuals were examined alive by clinical examination. Total body radiographs were taken of two birds, haematology and blood biochemistry results
were achieved in one bird. The birds either died immediately after clinical presentation or within
two days, two individuals were euthanized due to worsening of their clinical condition. All birds
underwent a post-mortem examination. While four birds were finally diagnosed with disseminated
xanthogranulomatosis, all six individuals had large eosinophilic intranuclear inclusion bodies in
the epithelial cells of the collecting ducts of the kidney and tested positive for PsAdV-2. Further
examinations are needed to clarify to what extent PsAdV-2 might elicit lipometabolic disease in birds,
or psittacines in general, and, in particular, the Red-crowned Parakeet.
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:92792 |
| Date | 25 July 2024 |
| Creators | Konicek, Cornelia, Heenemann, Kristin, Cramer, Kerstin, Vahlenkamp, Thomas W., Schmidt, Volker |
| Publisher | MDPI |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 2076-2615, 2316, 10.3390/ani12182316 |
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