Return to search

Lymphocytic 5'-ectonucleotidase : a marker of psychological stress-induced immune suppression / Jane Blake-Mortimer.

Addendum inserted (leaf 170 verso) / Some illustrations are on unnumbered leaves. / Bibliography: leaves 151-170. / xiv, 170, [25] leaves : ill. (some col.) ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Lymphocyte 5'-ectonucleotidase (NT) was selected as a mechanism to explain the phenomenon of stress-induced immunosuppression. The findings indicates that NT is a good marker of stress induced immune suppression and correlates negatively with depression scores such as the Beck Depression Inventory, and psychological distress as measured by the TMD scores, and STAI-trait. The suppression of NT appears to be mediated by reactive oxygen species (ROS), and is consistent with the finding of normal NT levels in melancholic patients with high antioxidant intake, the heightened inflammatory responses, the low levels of zinc, the low ascorbate stores, and the down regulation of glucocorticoid receptors reported to occur in stress/depressed patients. / Thesis (Ph.D.)--University of Adelaide, Dept. of Psychology, 1997?

Identiferoai:union.ndltd.org:ADTP/260072
Date January 1996
CreatorsBlake-Mortimer, Jane Suzanne
Source SetsAustraliasian Digital Theses Program
Languageen_US
Detected LanguageEnglish

Page generated in 0.002 seconds