Yes / MXenes (viz., transition metal carbides, carbonitrides, and nitrides) have
emerged as a new subclass of 2D materials. Due to their outstanding physicochemical
and biological properties, MXenes have gained much attention
in the biomedical field in recent years, including drug delivery systems,
regenerative medicine, and biosensing. Additionally, the incorporation
of MXenes into hydrogels has garnered significant interest in biomedical
engineering as an electroactive and mechanical nanoreinforcer capable of
converting nonconductive scaffolds into excellent conductors of electricity
with an impressive effect on mechanical properties for the engineering of
electroactive organs and tissues such as cardiac, skeletal muscle, and nerve.
However, many questions and problems remain unresolved that need to be
answered to usher these 2D materials toward their true destiny. Thus, this
review paper aims to provide an overview of the design and applications of
MXene-integrated composites for biomedical applications, including cardiac
tissue engineering, wound healing, infection therapy, cancer therapy, and
biosensors. Moreover, the current challenges and limitations of utilizing
MXenes in vivo are highlighted and discussed, followed by its prospects
as a guideline toward possible various futuristic biomedical applications.
This review article will inspire researchers, who search for properties,
opportunities, and challenges of using this 2D nanomaterial in biomedical
applications. / Open Access Funding provided by Istituto Italiano di Tecnologia within the CRUI-CARE Agreement.
| Identifer | oai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/19055 |
| Date | 07 July 2022 |
| Creators | Maleki, A., Ghomi, M., Nikfarjam, N., Akbari, M., Sharifi, E., Shahbazi, M-A., Kermanian, M., Seyedhamzeh, M., Zare, E.N., Mehrali, M., Moradi, O., Sefat, Farshid, Mattoli, V., Makvandi, P., Chen, Y. |
| Publisher | Wiley-VCH GmbH |
| Source Sets | Bradford Scholars |
| Language | English |
| Detected Language | English |
| Type | Article, Published version |
| Rights | © 2022 The Authors. Advanced Functional Materials published by Wiley-VCH GmbH. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited., CC-BY |
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