Concordance of objectively-detected retinal nerve fiber bundle defects in en face OCT images with conventional structural and functional changes in glaucoma.

Description

Yes / To assess how objectively-detected defects of retinal nerve fibre bundle (RNFB) reflectance in en face OCT images relate to circumpapillary retinal nerve fibre layer thickness (cpRNFLT) and visual field defects.
Cross-sectional study.
16 participants with early-glaucoma and 29 age-similar healthy controls, among which 22 had usable en face images to establish normative levels of RNFB reflectance.
All participants underwent cpRNFLT scans, visual field examination and wide-field OCT. En face reflectivity was assessed objectively using the Summary of Multiple Anatomically-Adjusted Slabs (SMAS) method. En face defects were deemed concordant with cpRNFLT when they had at least one cpRNFLT point with p

Links & Downloads

1. Cheloni R and Dennis J (2023) Concordance of objectively-detected retinal nerve fiber bundle defects in en face OCT images with conventional structural and functional changes in glaucoma. Ophthalmology Glaucoma. 6(1): 78-92.
2. http://hdl.handle.net/10454/19151
3. https://doi.org/10.1016/j.ogla.2022.07.001

Tags

En face OCT

Glaucoma

OCT

Retinal nerve fiber layer

Reflectance

Additional Fields

Identifer	oai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/19151
Date	15 September 2022
Creators	Cheloni, Riccardo, Denniss, Jonathan
Source Sets	Bradford Scholars
Language	English
Detected Language	English
Type	Article, Published version
Rights	(c) 2023 The Authors. This is an Open Access article distributed under the Creative Commons CC-BY license (https://creativecommons.org/licenses/by/4.0/), CC-BY