Objectives: As surgical experience with infective endocarditis following transcatheter aortic
valve replacement is scarce, this study compared the perioperative and short-term outcomes of patients
suffering from endocarditis following surgical aortic valve replacement and transcatheter aortic
valve replacement. Methods: Between January 2013 and December 2020, 468 consecutive patients
were admitted to our center for surgery for IE. Among them, 98 were operated on for endocarditis
following surgical aortic valve replacement and 22 for endocarditis following transcatheter aortic
valve replacement. Results: The median EuroSCORE II (52.1 (40.6–62.0) v/s 45.4 (32.6–58.1), p = 0.207)
and STS-PROM (1.8 (1.6–2.1) v/s 1.9 (1.4–2.2), p = 0.622) were comparable. Endocarditis following
transcatheter aortic valve replacement accounted for 13.7% of the aortic prosthetic valve endocarditis
between 2013 and 2015; this increased to 26.9% in the years 2019 and 2020.Concomitant procedures
were performed in 35 patients (29.2%). The operative mortality was 26.5% in the endocarditis following
surgical aortic valve replacement group and 9.1% in the endocarditis following transcatheter
aortic valve replacement group (p = 0.098). Upon follow-up, survival at 6 months was found to be
98% in the group with endocarditis following surgical aortic valve replacement and 89% in the group
with endocarditis following transcatheter aortic valve replacement (p = 0.081). Conclusions: Patients
suffering from endocarditis following surgical aortic valve replacement and transcatheter aortic valve
replacement present with comparable risk profiles and can be surgically treated with comparable
results. Surgery as a curative option should not be rejected even in this intermediate-risk cohort
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:87531 |
| Date | 20 October 2023 |
| Creators | Saha, Shekhar, Ali, Ahmad, Schnackenburg, Philip, Horke, Konstanze Maria, Oberbach, Andreas, Schlichting, Nadine, Sadoni, Sebastian, Rizas, Konstantinos, Braun, Daniel, Lühr, Maximilian, Bagaev, Erik, Hagl, Christian, Joskowiak, Dominik |
| Publisher | MDPI |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 3418 |
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