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Fundamentals of Hydrogel-Based Valves and Chemofluidic Transistors for Lab-on-a-Chip Technology: A Tutorial Review

Stimuli-sensitive hydrogels have an outstanding potential for miniaturized, integrated sensor, and actuator systems and especially for lab-on-chip technology, but the application is still in its infancy. One major reason may be that design and realization of hydrogel-based systems are exceptionally complex and demanding. Here, the design parameters of a key component, the hydrogel-based valve, are discussed in their entirety. Key developments in the fields of stimuli-sensitive hydrogels are highlighted and the necessary know-how in material behavior, microstructuring technologies, modeling and name five essential design guidelines as well as scaling laws for hydrogelbased components, including microfluidic one-directional valves, microelectromechanical systems valves, self-regulating, chemomechanical valves, and chemofluidic transistors, is provided.

Identiferoai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:88376
Date22 February 2024
CreatorsBeck, Anthony, Obst, Franziska, Gruner, Denise, Voigt, Andreas, Mehner, Philipp Jan, Gruenzner, Stefan, Koerbitz, René, Shahadha, Mohammed Hadi, Kutscher, Alexander, Paschew, Georgi, Marschner, Uwe, Richter, Andreas
PublisherWiley-VCH GmbH
Source SetsHochschulschriftenserver (HSSS) der SLUB Dresden
LanguageEnglish
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text
Rightsinfo:eu-repo/semantics/openAccess
Relation2365-709X, 10.1002/admt.202200417, info:eu-repo/grantAgreement/Bundesministerium für Bildung und Forschung/TransIC/03VP07530/, info:eu-repo/grantAgreement/Europäische Union | Freistaat Sachsen/CoV Guard/1633679941217/, info:eu-repo/grantAgreement/Freistaat Sachsen/NGScope/100390032 /, info:eu-repo/grantAgreement/Deutsche Forschungsgemeinschaft/Graduiertenkolleg/11944370//GRK 1865: Hydrogel-basierte Mikrosysteme

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