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Quantification and Classification of Cortical Perfusion during Ischemic Strokes by Intraoperative Thermal Imaging

Thermal imaging is a non-invasive and marker-free approach for intraoperative measurements of small temperature variations. In this work, we demonstrate the abilities of active dynamic thermal imaging for analysis of tissue perfusion state in case of cerebral ischemia. For this purpose, a NaCl irrigation is applied to the exposed cortex during hemicraniectomy. The cortical temperature changes are measured by a thermal imaging system and the thermal signal is recognized by a novel machine learning framework. Subsequent tissue heating is then approximated by a double exponential function to estimate tissue temperature decay constants. These constants allow us to characterize tissue with respect to its dynamic thermal properties. Using a Gaussian mixture model we show the correlation of these estimated parameters with infarct demarcations of post-operative CT. This novel scheme yields a standardized representation of cortical thermodynamic properties and might guide further research regarding specific intraoperative diagnostics.

Identiferoai:union.ndltd.org:DRESDEN/oai:qucosa.de:bsz:14-qucosa-230833
Date06 June 2018
CreatorsHoffmann, Nico, Drache, Georg, Koch, Edmund, Steiner, Gerald, Kirsch, Matthias, Petersohn, Uwe
ContributorsTechnische Universität Dresden, Fakultät Informatik
PublisherSaechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden
Source SetsHochschulschriftenserver (HSSS) der SLUB Dresden
LanguageEnglish
Detected LanguageEnglish
Typedoc-type:workingPaper
Formatapplication/pdf
Relationdcterms:isPartOf:Technische Berichte / Technische Universität Dresden, Fakultät Informatik; 2016,02 (TUD-FI16-02-September 2016)

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