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Non-Occlusive St-Segment Elevated Myocardial Infarction Following the Administration of Liposomal Amphotericin B in the Treatment of Cryptococcal Meningitis

What is known and objective: Liposomal amphotericin B (L-AmB) is the cornerstone of many serious invasive fungal infections. Despite lower frequencies of commonly reported adverse events in clinical trials compared to conventional formulations, post-marketing complications continue to mount. Case description: We present a case of chest pain following the initial dose of L-AmB for cryptococcal meningitis. Electrocardiogram demonstrated no acute electrocardiogram findings. Upon rechallenge, the chest pain worsened was subsequently accompanied by ST-segment elevation. Emergent coronary angiography found no acute findings. What is new and conclusion: Providers should be aware of cardiac complications with L-AmB, including non-occlusive ST-segment elevation.

Identiferoai:union.ndltd.org:ETSU/oai:dc.etsu.edu:etsu-works-10594
Date01 October 2020
CreatorsKullab, Susan M., Patel, Paras D., Lewis, Paul O.
PublisherDigital Commons @ East Tennessee State University
Source SetsEast Tennessee State University
Detected LanguageEnglish
Typetext
SourceETSU Faculty Works

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