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Previous issue date: 2016-08-31 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) / Devido ? alta preval?ncia de doen?as bucais, como a c?rie dent?ria, e ao elevado potencial terap?utico de mat?rias-primas vegetais, reconhecendo o Brasil como um pa?s de grande variedade etnobot?nica, a presente pesquisa buscou analisar fitoquimicamente o material vegetal e determinar a a??o antibacteriana do extrato de Spondias mombin L. (caj?) sobre bact?rias bucais planct?nicas. Para isso foram realizadas a prospec??o fitoqu?mica do material vegetal, a determina??o da Concentra??o Inibit?ria M?nima (CIM) e da Concentra??o Inibit?ria M?nima de Ader?ncia (CIMA) do extrato de Spondias mombin L. (caj?) e do digluconato de clorexidina a 0,12% (controle) frente ?s bact?rias S. mutans e S. oralis bem como a cin?tica bactericida das referidas subst?ncias (teste e controle) sobre o S. mutans. Os resultados revelaram que tal extrato inibiu o crescimento bacteriano em todas as concentra??es testadas na CIM, al?m de ter impedido a ader?ncia dos microrganismos ? parede do tudo de vidro tamb?m at? a concentra??o de 1:512 do extrato, mostrando-se superior, nessas duas an?lises, ao digluconato de clorexidina a 0,12%. Observou-se tamb?m que o extrato bruto de Spondias mombin L. j? demosntrou a??o bactericida ap?s duas horas de contato com o S. mutans, enquanto o mesmo extrato, em sua concentra??o inibit?ria m?nima, exibiu efeito bactericida somente ap?s quatro horas de contato com tal microrganismo. Dessa forma, conclui-se que: o extrato de Spondias monbim L. se mostra bastante promissor como agente bactericida frente ao S. mutans e S. oralis quando comparado ao digluconato de clorexidina. / Due to the high prevalence of oral diseases and the considerable therapeutic potential of vegetable raw materials, and based on the fact that Brazil is a country of great ethnobotanic variety, the present study sought to phytochemically analyze plant material, as well as determine the antibacterial action of the extract of Spondias mombin L. (caja) on oral planktonic bacteria. To achieve this, phytochemical screening of the plant material was performed, along with the determination of the Minimum Inhibitory Concentration (MIC) and the Minimum Inhibitory Concentration of Adherence (MICA) of Spondias mombin L. extract (caja) against S. mutans and S. oralis, and the bactericidal kinetic extract on S. mutans. It was found that the extract inhibited bacterial growth at all the MICs tested, and prevented the adhesion of the microorganisms to the glass wall at a concentration of 1:512 of the extract. As such it was more effective in these two tests than 0.12% chlorhexidine gluconate. It was also found that crude extract of Spondias mombin L. exhibited antibacterial action after two hours of contact with S. mutans, while the extract in its minimum inhibitory concentration displayed a bactericidal effect after four hours of contact time with S. mutans. Thus, it is concluded that: the Spondias mombin L. extract is shown quite promising as a bactericide against Streptococcus mutans and S. oralis compared to chlorhexidine digluconate.
| Identifer | oai:union.ndltd.org:IBICT/oai:repositorio.ufrn.br:123456789/22022 |
| Date | 31 August 2016 |
| Creators | Lima, Emanuelle Louyde Ferreira de |
| Contributors | 87808838420, Assun??o, Isauremi Vieira de, 66427983415, Gad? Neto, C?cero Rom?o, 50430947453, Lins, Ruthineia Di?genes Alves Uchoa |
| Publisher | PROGRAMA DE P?S-GRADUA??O EM SA?DE COLETIVA, UFRN, Brasil |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Source | reponame:Repositório Institucional da UFRN, instname:Universidade Federal do Rio Grande do Norte, instacron:UFRN |
| Rights | info:eu-repo/semantics/openAccess |
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