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Previous issue date: 2015-03-30 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / Objective: to evaluate the volume of the spleen in eutrophic and obese adolescents through MR and to compare it between the two groups. Secondarily, these measurements were correlated with the age, sex, weight, BMI and height of the patients in each group.
Material and Methods: a cross-sectional, observational study, part of an umbrella project, performed during January and February 2015 in a tertiary hospital. The following were measured: the maximum width (W) and thickness (T) of the spleen in the T1 axial sequence and the maximum longitudinal diameter (LD) in the T2 coronal sequence from MR exams of the upper abdomen performed on 50 adolescents between the ages of 16 and 18. The adolescents were divided into two groups: eutrophic subjects (BMI<25) and overweight/obese subjects (BMI ?25). We calculated the volume of each patient?s organ through the conventional formula to calculate the volume of an elongated ellipsoid (0.524 x W x T x LD). Anthropometric data (weight, BMI, height and age) were obtained from the umbrella project?s database. We used Pearson or Spearman correlation coefficients to correlate the quantitative variables with each other and Student?s t-test to compare the averages for independent samples.
Results: Twenty-six patients (52.0%) were male; the average age was 16.7 years old, and standard deviation was 0.8 years; 31 patients (82.0%) had a BMI<25 (eutrophic) and 19 (38%) had a BMI?25 (overweight/obese). There was a statistically significant difference between the groups for the spleen?s width (p=0.008) and volume (p=0.020), which were larger in the overweight/obese group. For the eutrophic group, the averages for the maximum width (p=0.016), for the maximum longitudinal diameter (p <0.001) and for the volume of the spleen (p=0,001) were higher in the males than in the females in a statistically significant way. There was no statistically significant difference in the measurements between the sexes for the overweight/obese group. Height showed a stronger correlation than weight with the volume, maximum width and maximum longitudinal diameter of the spleen in the eutrophic group and a correlation of the same intensity with weight for all the measurements of the spleen in the overweight/obese group.
Conclusion: This study suggests that the volume of the spleen as determined by MR is greater in overweight or obese adolescents than it is in eutrophic adolescents. More research is needed to evaluate the reproducibility of our results on the rest of the adolescent population, given the narrow age band used for our study. / Objetivo: avaliar o volume do ba?o em adolescentes eutr?ficos e obesos atrav?s da RM e compar?-lo entre os dois grupos. Secundariamente, estas medidas ser?o correlacionadas com a idade, o sexo, o peso, o IMC, e a altura dos pacientes em cada um dos grupos.
Material e M?todos: estudo observacional transversal, parte de um projeto guarda-chuva, realizado em janeiro e fevereiro de 2015 em um hospital terci?rio; foram realizadas as medidas da largura m?xima (L) e da espessura (E) do ba?o na sequ?ncia axial T1 e do di?metro longitudinal m?ximo (DL) na sequ?ncia coronal T2 de exames de RM do abd?men superior de 50 adolescentes entre 16 e 18 anos divididos em dois grupos: eutr?ficos (IMC<25) e sobrepeso/obesos (IMC ?25); o volume do ?rg?o de cada paciente foi calculado atrav?s da f?rmula convencional para calcular o volume de um elips?ide alongado (0,524 x L x E x DL); os dados antropom?tricos (peso, IMC, altura e idade) foram obtidos do banco de dados do projeto guarda-chuva; para correlacionar as vari?veis quantitativas entre si foram utilizados os coeficientes de correla??o de Pearson ou Spearman e para comparar as m?dias foi utilizado o teste t de Student para amostras independentes.
Resultados: 26 pacientes (52,0%) eram do sexo masculino; a m?dia de idade foi de 16,7 anos e o desvio-padr?o de 0,8 anos; trinta e um pacientes (82,0%) tinham IMC<25 (eutr?ficos) e 19 (38%) tinham IMC?25 (sobrepeso/obesos); a largura (p=0,008) e o volume do ba?o (p=0,020) apresentaram diferen?a estatisticamente significativa entre os grupos, sendo maiores no grupo sobrepeso/obesos; a m?dia da largura m?xima (p=0,016), do di?metro longitudinal m?ximo (p <0,001) e do volume do ba?o (p=0,001) foram maiores no sexo masculino do que no feminino de forma estatisticamente significativa no grupo dos eutr?ficos e n?o houve diferen?a significativa entre os sexos no grupo sobrepeso/obesos; a altura apresentou correla??o mais forte do que o peso com o volume, a largura m?xima e o di?metro longitudinal m?ximo do ba?o no grupo dos pacientes eutr?ficos e correla??o de mesma intensidade que o peso com todas as medidas do ba?o no grupo sobrepeso/obesos.
Conclus?o: Este estudo sugere que o volume do ba?o aferido atrav?s da RM ? maior em adolescentes com sobrepeso e obesos do que em adolescentes eutr?ficos. S?o necess?rios mais trabalhos que avaliem a reprodutibilidade dos nossos resultados no restante da popula??o pedi?trica, tendo em vista a estreita faixa et?ria do nosso estudo.
| Identifer | oai:union.ndltd.org:IBICT/oai:tede2.pucrs.br:tede/6000 |
| Date | 30 March 2015 |
| Creators | Cunha, Carol Fernandes Jerzewski Sotero da |
| Contributors | Baldisserotto, Matteo |
| Publisher | Pontif?cia Universidade Cat?lica do Rio Grande do Sul, Programa de P?s-Gradua??o em Medicina/Pediatria e Sa?de da Crian?a, PUCRS, Brasil, Faculdade de Medicina |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Format | application/pdf |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da PUC_RS, instname:Pontifícia Universidade Católica do Rio Grande do Sul, instacron:PUC_RS |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 3098206005268432148, 600, 600, 600, 600, -8624664729441623247, -969369452308786627, 2075167498588264571 |
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