Doctor of Philosophy / Department of Human Nutrition / Mark D. Haub / Objective: The objective was to compare the postprandial glycemic and insulinemic responses to nutrition bars containing either cross-linked RS type 4 (RS4[subscript]XL)
or standard wheat starch in normoglycemic adults (n=13; age= 27±5 yr; BMI=25±3
kg/m²).
Methods: Volunteers completed three trials during which they consumed a
glucose beverage (GLU), a puffed wheat control bar (PWB), and a bar containing RS4[subscript]XL
matched for available carbohydrate content. Serial blood samples were collected over
two hours and glucose and insulin concentrations were determined and the incremental
area under the curve (iAUC) was calculated.
Results: The RS4[subscript]XL peak glucose and insulin concentrations were lower than the
GLU and PWB (p<0.05). The iAUC for glucose and insulin were lower following
ingestion of RS4[subscript]XL compared with the GLU and PWB trials.
Conclusions: These data illustrate, for the first time, that directly substituting
standard starch with RS4[subscript]XL, while matched for available carbohydrates, attenuated
postprandial glucose and insulin levels in humans. It remains to be determined
whether this response was due to the dietary fiber and/or resistant starch aspects of the
RS4[subscript]XL bar.
Keywords: insulin sensitivity, diabetes, dietary fiber, prebiotic, glycemic index
| Identifer | oai:union.ndltd.org:KSU/oai:krex.k-state.edu:2097/4220 |
| Date | January 1900 |
| Creators | Al-Tamimi, Enas K. |
| Publisher | Kansas State University |
| Source Sets | K-State Research Exchange |
| Language | en_US |
| Detected Language | English |
| Type | Dissertation |
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