This thesis presents two experimental microelectronic prototypes for neurophysiological
applications. Both systems target diagnostics and treatment of neurological disorders,
and they are experimentally validated in vivo by online intracranial EEG recording
in freely moving rats.
The first prototype is a 56-channel chopper-stabilized low-noise neural recording
interface IC with programmable mixed-signal DC cancellation feedback, fabricated in
a 0.13μm CMOS process. Each recording channel has a low-noise fully-differential
amplifier, and a digital integrator and a delta-sigma DAC in the feedback to cancel DC
offsets of up to ±50mV. Chopper stabilization technique is used to reduce the amplifier
flicker noise. The recorded signals are digitized by 7 column-parallel SAR ADCs.
The second prototype is a compact headset for multi-site neuromonitoring and neurostimulation
in rodent brain. A stack of 2 mini-PCBs was designed and experimentally
validated. It includes a previously fabricated 0.35μm CMOS recording and stimulation
IC, a low-power FPGA, and the IC peripherals.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:OTU.1807/42678 |
| Date | 21 November 2013 |
| Creators | Bagheri, Arezu |
| Contributors | Genov, Roman |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | en_ca |
| Detected Language | English |
| Type | Thesis |
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