The locomotor behavior of adult rats (n = 48) at different age periods was determined on five inclined plexiglass runways of different widths (24, 18, 12, 6 and 3 mm). Differences in the number (old middle-age $>$ young) were observed between the three age groups. For a subset of animals (n = 17), age-related changes were examined in the organization of the morphological properties of horseradish peroxidase (HRP)-labelled motoneurons in a representative hindlimb motoneuron pool. Data suggests that the loss of large motoneurons and soma atrophy play a role (p $<$ 0.01) in the organization of the medial gastrocnemius (MG) motoneuron pool in aged animals. The relationship between the composite motor performance score and the number of MG alpha motoneurons for individual animals reflected the continuum from young to old.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.22712 |
| Date | January 1995 |
| Creators | Partidas, Martha Helena |
| Contributors | Noven, Sharyn Vanden (advisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science (School of Physical and Occupational Therapy.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 001453641, proquestno: MM05520, Theses scanned by UMI/ProQuest. |
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