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Characterization of the gut microbiota in diabetes mellitus II patients with adequate and inadequate metabolic control

El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado. / Objective: The objective of this study was to characterize the composition of the gut microbiota in type 2 Diabetes Mellitus (T2DM) patients with adequate and inadequate metabolic control, and its relationship with fiber consumption. Results: A total of 26 patients with type 2 diabetes mellitus (T2DM) were enrolled, of which 7 (26.9%) cases had adequate metabolic control (HbA1c < 7%) and 19 (73.1%) inadequate metabolic control (HbA1c ≥ 7%). It was observed that among patients with controlled T2DM, 2 (28.6%) cases presented good intake of fiber and 5 (71.4%) cases a regular intake. In contrast, in patients with uncontrolled T2DM, 13 (68.4%) patients reported a regular intake and 6 (31.6%) a poor intake. In relation to the identification of the gut microbiota, both groups presented a similar characterization. There were differences in the population of bacteria identified in both groups, however, the results were not statistically significant. The most frequently identified bacteria in controlled and uncontrolled T2DM patients were Prevotella (71.4% vs 52.6%), followed by Firmicutes (71.4% vs 42.1%), Proteobacteria (71.4% vs 36.8%) and Bacteroidetes (57.1% vs 37.8%). On the other hand, Fusobacterium, Actinobacteria were not identified in either of the two groups of study. / Revisión por pares

Identiferoai:union.ndltd.org:PERUUPC/oai:repositorioacademico.upc.edu.pe:10757/657331
Date01 December 2021
CreatorsHamasaki-Matos, Angie Joyce, Cóndor-Marín, Katherine Marlene, Aquino-Ortega, Ronald, Carrillo-Ng, Hugo, Ugarte-Gil, Cesar, Silva-Caso, Wilmer, Aguilar-Luis, Miguel Angel, del Valle-Mendoza, Juana
PublisherBioMed Central Ltd
Source SetsUniversidad Peruana de Ciencias Aplicadas (UPC)
LanguageEnglish
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/article
Formatapplication/html
SourceUniversidad Peruana de Ciencias Aplicadas (UPC), Repositorio Académico - UPC, BMC Research Notes, 14, 1
Rightsinfo:eu-repo/semantics/embargoedAccess
Relationhttps://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-021-05655-z

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