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Physiological Markers of Stress Generation and Affect Reactivity in Depression

Although existing research has evaluated physiological and environmental risk factors for depression, these processes are often examined in isolation without considering the dynamic relationships in risk for depression. The present study evaluated physiological markers of resting and stress-reactive respiratory sinus arrhythmia (RSA and RSA reactivity) as predictors of depressive symptoms and interpersonal stress generation, a mutable and potent vulnerability for depression. Further, we examined whether stress generation predicted subsequent depressive symptoms. In a sample of late adolescents (N = 105; 18-22 years; 76% female), individuals who screened in for a history of clinical and subclinical depression participated in a micro-longitudinal assessment with a diagnostic interview, in-laboratory socio-evaluative stressor task, and two weeks of daily assessments of stressful events and depressive symptoms. First, results indicated that there were no clinical or physiological differences between individuals with a clinical or subclinical depression history. Our multilevel modeling analyses revealed that: 1) only lower levels of resting RSA predicted depressive symptoms over the two-week period; 2) only lower RSA reactivity predicted greater interpersonal stress generation, but not independent stressors; 3) interpersonal stress generation mediated the relationship between RSA reactivity and depressive symptoms, but not resting RSA and depressive symptoms; 4) sex differences only occurred in the relationship between resting RSA and depressive symptoms; and 5) there were no interactive effects of resting RSA and RSA reactivity on depression or interpersonal stress generation. These findings highlight the importance of assessing both resting RSA and RSA reactivity in the examination of depression and depression-related processes. / Psychology

Identiferoai:union.ndltd.org:TEMPLE/oai:scholarshare.temple.edu:20.500.12613/1375
Date January 2017
CreatorsHamilton, Jessica Leigh
ContributorsAlloy, Lauren B., Olino, Thomas, Drabick, Deborah A., Giovannetti, Tania, Kendall, Philip C., Johnson, Kareem
PublisherTemple University. Libraries
Source SetsTemple University
LanguageEnglish
Detected LanguageEnglish
TypeThesis/Dissertation, Text
Format127 pages
RightsIN COPYRIGHT- This Rights Statement can be used for an Item that is in copyright. Using this statement implies that the organization making this Item available has determined that the Item is in copyright and either is the rights-holder, has obtained permission from the rights-holder(s) to make their Work(s) available, or makes the Item available under an exception or limitation to copyright (including Fair Use) that entitles it to make the Item available., http://rightsstatements.org/vocab/InC/1.0/
Relationhttp://dx.doi.org/10.34944/dspace/1357, Theses and Dissertations

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