The development of wearable
devices to monitor biosignals and collect real-time data from biological systems
at all scales from cellular to organ level has played a significant role in the
field of medical engineering. The current coronavirus disease 2019 (COVID-19)
pandemic has further increased the demand for remote monitoring and smart
healthcare where patient data can be also be accessed from a remote distance. Recent
efforts to integrate wearable devices with artificial intelligence and machine
learning have transformed conventional healthcare into smart healthcare, which
requires reliable and robust recording data. The biomedical devices that are
mechanically stretchable and compliant have provided the capability to form a
seamless interface with the curvilinear, soft surface of tissues and body, enabling
accurate, continuous acquisition of physical and electrophysiological signals.
This dissertation presents a comprehensive set of functional materials, design
principles, and fabrication strategies to develop mechanically stretchable and
compliant biomedical devices tailored for various applications, including (1) a
stretchable sensor patch enabling the continuous monitoring of swallowing
function from the submental/facial area for the telerehabilitation of patients
with dysphagia, (2) a human hand-like sensory glove for advanced control of
prosthetic hands, (3) a mechanically compliant manipulator for the non-invasive
handling of delicate biomaterials and bioelectronics, and (4) a stretchable
sensors embedded inside a tissue scaffold enabling the continuous monitoring of
cellular electrophysiological behavior with high spatiotemporal resolution.<br>
| Identifer | oai:union.ndltd.org:purdue.edu/oai:figshare.com:article/14486700 |
| Date | 27 April 2021 |
| Creators | Min Ku Kim (10701789) |
| Source Sets | Purdue University |
| Detected Language | English |
| Type | Text, Thesis |
| Rights | CC BY 4.0 |
| Relation | https://figshare.com/articles/thesis/DESIGN_PRINCIPLES_OF_STRETCHABLE_AND_COMPLIANT_ELECTROMECHANICAL_DEVICES_FOR_BIOMEDICAL_APPLICATIONS/14486700 |
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