Return to search

Mechanics of nonlinear biomembranes: application to ophthalmology

Changes in the mechanics of the lens capsule of the eye arising from alterations of
its native configuration can lead to undesirable clinical results. One example is the
surgical introduction of a hole into the lens capsule and subsequent removal of the cloudy
lens during cataract surgery. The adverse effect is secondary cataract on the posterior lens
capsule, brought about by a sudden proliferation of lens epithelial cells in the region.
Understanding the biomechanics of the anterior lens capsule is necessary in order to
model its behavior under various physiological conditions and predict its response to
alterations and perturbations such as those during cataract surgery. Such knowledge will
help in the improvement of techniques during cataract surgery, and in the design of
artificial intraocular lens.
In this study we present, for the first time, results that demonstrate that the
anterior lens capsule exhibits non-homogeneity and regionally varying anisotropy. We
also compute stresses in the lens capsule due to normal loading conditions and
procedures such as a capsulorhexis.

Identiferoai:union.ndltd.org:tamu.edu/oai:repository.tamu.edu:1969.1/5001
Date25 April 2007
CreatorsDavid, Fredegusto Guido
ContributorsHumphrey, Jay D.
PublisherTexas A&M University
Source SetsTexas A and M University
Languageen_US
Detected LanguageEnglish
TypeBook, Thesis, Electronic Dissertation, text
Format1283400 bytes, electronic, application/pdf, born digital

Page generated in 0.0056 seconds