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Study of aerosol transport and deposition in the lungs using computational fluid dynamics (CFD)

We have studied gas flow and particle deposition in a realistic three-dimensional model of the bronchial tree, extending from the trachea to the segmental bronchi (7th airway generation for the most distal ones) using Computational Fluid Dynamics (CFD). The model is based on the morphometrical data of Horsfield et al. [J. Appl. Physiol. 31: 207-217, 1971] and on bronchoscopic and CT images, which give the spatial 3D-orientation of the curved ducts. It incorporates realistic angles of successive branching planes. Steady inspiratory flow varying between 50cm³/s and 500cm³/s was simulated as well as deposition of spherical aerosol particles (1 to 7& / Doctorat en sciences appliquées / info:eu-repo/semantics/nonPublished

Identiferoai:union.ndltd.org:ulb.ac.be/oai:dipot.ulb.ac.be:2013/211037
Date20 June 2005
CreatorsErtbruggen, Caroline van
ContributorsPaiva, Manuel, Leduc, Bernard, Hendrick, Patrick, Degrez, Gérard, Hirsch, Charles, Riethmuller, Michel M.L.
PublisherUniversite Libre de Bruxelles, Université libre de Bruxelles, Faculté de Médecine – Médecine, Bruxelles
Source SetsUniversité libre de Bruxelles
LanguageFrench
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/doctoralThesis, info:ulb-repo/semantics/doctoralThesis, info:ulb-repo/semantics/openurl/vlink-dissertation
Format1 v. (VII ,354 p.), No full-text files

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