Thesis--Göttingen. / Cover title. Vita. Bibliography: p. v-vii.

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D’emblée, l’Holocauste fut perçu comme le choc moral et politique le plus radical du vingtième siècle. Des nombreux intellectuels à s’être penchés sur cette question p o u r tenter d’en comprendre le sens, Theodor W. Adomo et Hannah Arendt sont, sans contredit, parmi les plus importants. Ce mémoire explore l ’interprétation philosophique que donnèrent Adomo et Arendt de cet événement. Mettant ces deux auteurs en parallèle dans le but de faire ressortir les convergences et les divergences de leurs pensées, il analyse la place et le rôle que joue l ’Holocauste dans celles-ci. Les grandes lignes de leurs analyses, qui consistent à rattache r l ’Holocauste aux conditions d ’existence propres à la modernité et à souligner to u t ce q u ’un tel lien comporte de potentiel critique, connaîtront un destin brillant : Adomo et Arendt constituent, jusqu’à ce jour, des incontournables dans l ’analyse philosophique de l ’Holocauste et de la domination politique en général.

Inaug.-diss.--Bern. / Curriculum vitae. Pub. also under title: Chr. W. Dohm, der gegner der physiokratie und seine thesen. Berlin, 1908. "Anhang" (Bibliography) p. [134]-143.

Inaug.-diss.--Bern. / Curriculum vitae. Pub. also under title: Chr. W. Dohm, der gegner der physiokratie und seine thesen. Berlin, 1908. "Anhang" (Bibliography) p. [134]-143.

The evolutionary status of the hot R CrB stars has long remained a matter of conjecture, primarily because of the relative dearth of relevant observational material. Previously the group had been thought to occupy a position intermediate in status between the EHe and R CrB classes as they have (at least at first glance) observational properties in common with both types of object. The photosphere of DY Cen has been quantitatively confirmed to be hydrogen-deficient and photometric variations suggest the star undergoes short period pulsations. Using a period-temperature relation applicable to hydrogen-deficient stars it would appear that this object has similar physical properties to both the EHe and R CrB stars. Narrow band imaging of V348 Sgr has shown that the associated nebula exhibits a bipolar structure and therefore must be closely related to planetary nebulae rather than H II regions. Spectroscopic observations have proved that the star in its present evolutionary state is incapable of ionising the nebula. Several scenarios for this behaviour are briefly discussed. The large helium enrichment found in the nebula indicates that processed material must have been ejected during the last major episode of mass loss. Evidence is presented that suggests a strong hydrogen abundance gradient exists within the nebula. A novel technique has been developed for determining reddening distances. Its main advantage over other similar methods is that both early and late-type stars may be used to establish the reddening-distance relationship. With more development this technique may prove to be an important tool in distance determinations for objects such as planetary nebulae etc. This technique was used to derive a distance of (4. 7±1.0) kpc for V348 Sgr. Using the core-mass relation for hydrogen-deficient stars implies that both V348 Sgr and MV Sgr are lower mass and luminosity objects than EHe and R CrB stars. The evidence presented in this thesis indicates that the hot R CrB group is not a homogeneous one. DY Cen is much more luminous and massive than the other members. The mass and luminosity of V348 Sgr and MV Sgr are consistent with the scenario that both have recently suffered a thermal pulse (causing re-ignition of a helium burning shell) and are currently looping back to the R CrB domain of the H R diagram.

Nell’ambito della linguistica storica inglese si è assistito solo negli ultimi anni all’emergere di un nuovo interesse accademico e al conseguente sviluppo di un nuovo campo di ricerca: il Late(r) Modern English (LModE). Lo studio diacronico della lingua inglese, tradizionalmente spintosi fino a includere il periodo dell’Early Modern English, ha infatti solo recentemente accolto nel suo raggio d’indagine lo studio dei secoli a noi più vicini, il XVIII e il XIX, precedentemente soprannominati “the Cinderellas of English historical linguistic study” (Jones 1989). Il presente lavoro propone un’analisi storica e sociolinguistica del periodo che considera l’evoluzione linguistica del British English, l’importante fenomeno del prescrittivismo linguistico e lo sviluppo della grammatografia inglese nel XVIII secolo. Il primo capitolo propone una collocazione temporale del LModE tra il 1660 e il 1945, ne traccia i principali sviluppi storici e sociali, e presenta lo stato dell’arte sulla variazione linguistica del periodo. Il secondo capitolo presenta un’analisi approfondita delle diverse ideologie che hanno contribuito allo sviluppo del prescrittivismo quale fenomeno linguisticamente e culturalmente pervasivo. Il terzo capitolo, infine, traccia lo sviluppo settecentesco della grammatica come genere normativo e presenta l’analisi dettagliata di un'opera finora poco osservata: “Grammatical Observations on the English Language” (1766) del reverendo Caleb Fleming (1698-1779). / A growing amount of scholarly attention has been paid to Late(r) Modern English since Jones (1989) famously dubbed the eighteenth and nineteenth centuries “the Cinderellas of English historical linguistic study”. The present work aims to contribute to such process of “De-Cinderellisation” (Rodriguez-Alvarez & Rodriguez-Gil 2011) through a historical and sociolinguistic account that links the evolution of British English in modern times to the rise of linguistic normativism and the development of grammars. The first chapter frames the period between 1660 and 1945, reports on the major socio-historical developments of the time, and tracks the linguistic variation through a state-of-the-art survey. The second chapter offers a lengthy and thorough examination of the different ideologies which brought about the all-pervasive linguistic and cultural phenomenon of prescriptivism. Finally the third chapter details the eighteenth-century development of English grammars as a normative genre and focuses on the micro-level analysis of the under-researched work by Rev. Caleb Fleming (1698-1779): “Grammatical Observations on the English Language” (1766).

Orientador : Prof. Dr. Obdulio Gomes Miguel / Co-orientadora : Profª. Drª. Marilis Dallarmi Miguel / Tese (doutorado) - Universidade Federal do Paraná, Setor de Ciências da Saúde, Programa de Pós-Graduação em Ciências Farmacêuticas. Defesa: Curitiba, 27/11/2014 / Inclui referências / Área de concentração: Insumos, medicamentos e correlatos / Resumo: Espécies vegetais são utilizadas ao longo da história da humanidade como recurso para cura e alívio dos mais diversos males. O conhecimento empírico a respeito de diferentes espécies vegetais se tornou uma ferramenta importante na descoberta de substâncias que possam fazer parte do arsenal terapêutico. Baseados nessa premissa o presente trabalho tem como objetivo verificar as informações acerca de atividades biológicas e traçar perfil fitoquímico da espécie vegetal amazônica – Byrsonima duckeana W. R. Anderson. O perfil fitoquímico delineou metabólitos secundários de interesse biológico, tais como a presença de flavonóides, esteróides, terpenos e taninos. O perfil cromatográfico constatou a presença de ácido gálico e as técnicas de elucidação estrutural permitiram que se constatasse a presença do terpeno Friedelina. Na busca por atividades biológicas e farmacológicas, a espécie apresentou atividades de grande interesse, com grande potencial antioxidante e baixa toxicidade, dada a ausência de citotoxicidade no modelo Artemia salina e no ensaio in vivo de toxicidade aguda. Os ensaios farmacológicos demonstraram atividade antiinflamatória e analgésica, em especial para a fração acetato de etila, corroborando com estudos de outras espécies do gênero. Foi encontrada ainda atividade citotóxica no modelo de cultura celular, em células HT29 e atividade hemolítica. Dessa forma, Byrsonima duckeana mostrou ser uma espécie interessante químicamente e farmacologicamente. Palavras-chave: Byrsonima duckeana W.R. Anderson, Farmacologia, Antioxidante, Amazônia, Citotoxicidade. / Abstract: Plant species are used throughout the history of mankind as a resource for healing and relief from various ailments . Empirical knowledge about different plant species has become an important tool in the discovery of substances which may form part of the therapeutic arsenal. Based on this premise this study aims to determine information about the biological activities and tracing phytochemical profile of Amazonian plant species - duckeana Byrsonima WR Anderson. The phytochemical profile outlined secondary metabolites of biological interest , such as the presence of flavonoids , steroids , terpenoids and tannins . The chromatographic profile showed the presence of gallic acid and structural elucidation techniques have allowed it appeared the presence of terpene friedelin . In the search for biological and pharmacological activities , the species was of great interest activities with great antioxidant potential and low toxicity , given the absence of cytotoxicity in the model brine shrimp assay and in vivo acute toxicity . Pharmacological studies demonstrated anti-inflammatory and analgesic activity , especially for the ethyl acetate fraction , corroborating studies of other species of the genus . Cytotoxic activity was also found in the cell culture model , in HT29 cells and low hemolytic activity . Thus , Byrsonima duckeana proved to be an interesting specie chemically and pharmacologically. Keywords : Byrsonima duckeana W.R Anderson, Pharmacology, Antioxidant, Amazon, Cytotoxicity .