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What do newly diagnosed patients have to say regarding their preparation and ongoing needs during the experience of chemotherapy?Palmer, April. January 2009 (has links)
Thesis (M.S.)--California State University, Chico. / Includes abstract. "Located in the Chico Digital Repository." Includes bibliographical references (p. 35-38).
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Predictors of changes in health-related quality of life during chemotherapy in an advanced non-small cell lung cancer patient populationShallwani, Shirin Mehdi January 2009 (has links)
1 volume
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Studies toward the synthesis of 3,6-bis-(5-chloro-2-piperidyl)-2, 5-piperazinedioneMoreland, Margaret. January 1979 (has links)
The naturally occurring compound 3,6-bis-(5-chloro-2-piperidyl)-2,5-piperazinedione (1) is a promising new antitumor drug. The mechanisms of action of antitumor alkylating agents, particularly the nitrogen mustards and sesquiterpene lactones, suggest possible modes of antitumor activity of compound 1. A possible synthetic scheme for compound 1 is developed by consideration of methods of synthesis of piperidines, (alpha)-substituted-(alpha),(beta)-unsaturated esters, and (beta)-amino alcohols. / A synthesis of (alpha)-chloro-(alpha),(beta)-unsaturated esters from carbonyl compounds and t-butyl (alpha)-chloro-(alpha)-trimethylsilyl acetate is developed. Oxyamination of the terminal double bond of t-butyl 2-chloro-2,6-heptadienoate occurs by epoxidation and reaction with an amine or azide ion and by osmium tetroxide catalyzed reaction with Chloramine-T. The piperidine ring is formed by an internal Michael raction of t-butyl 2-chloro-6-t-butyldimethylsilyloxy-7-tosylamino-2-heptenoate. The amino acid (1-tosyl-5-hydroxy-2-piperidyl) glycine is synthesized and found to be unstable to acidic esterification conditions. / Strategies for overcoming the problems encountered in the synthesis are discussed.
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Studies toward the synthesis of 3,6-bis-(5-chloro-2-piperidyl)-2, 5-piperazinedioneMoreland, Margaret. January 1979 (has links)
No description available.
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Azoreductases in cancer therapySims, Margaret Alison January 1994 (has links)
No description available.
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Protentiation of methotrexate cytotoxicity by indomethacinHollingsworth, Simon John January 1993 (has links)
No description available.
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The effects of sequence selective antitumour antibiotics on DNA structureWaterloh, Kerstin January 1991 (has links)
No description available.
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A study of nephrotoxicity caused by cytotoxic drugs in children with cancerSkinner, Roderick January 1994 (has links)
No description available.
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The clinical and cellular pharmacology of carboplatin in relation to toxicity and response in epithelial ovarian cancerAswad, Saad Ghazal January 1994 (has links)
No description available.
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The metabolism and potential toxicity mechanisms of thiotepaHoefer, Constance C. January 1995 (has links)
No description available.
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