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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
111

Modulation of the myelopoietic support function of murine bone marrow stroma by ionising radiation : the role of soluble mediators and the effects of putative radioprotective agents

Cooper, Simon James January 1998 (has links)
No description available.
112

Longitudinal data models for evaluating change in prescribing patterns

Sithole, Jabulani S. January 2000 (has links)
No description available.
113

Application of survival methods for the analysis of adverse event data

Mason, Tracey January 1999 (has links)
The concept of collecting Adverse Events (AEs) arose with the advent of the Thalidomide incident. Prior to this the development and marketing of drugs was not regulated in any way. It was the teterogenic effects which raised people's awareness of the damage prescription drugs could cause. This thesis will begin by describing the background to the foundation of the Committee for the Safety of Medicines (CSM) and how AEs are collected today. This thesis will investigate survival analysis, discriminant analysis and logistic regression to identify prognostic indicators. These indicators will be developed to build, assess and compare predictor models produced to see if the factors identified are similar amongst the methodologies used and if so are the background assumptions valid in this case. ROC analysis will be used to classify the prognostic indices produced by a valid cut-off point, in many medical applications the emphasis is on creating the index - the cut-off points are chosen by clinical judgement. Here ROC analysis is used to give a statistical background to the decision. In addition neural networks will be investigated and compared to the other models. Two sets of data are explored within the thesis, firstly data from a Phase III clinical trial used to assess the efficacy and safety of a new drug used to repress the advance of Alzheimer's disease where AEs are collected routinely and secondly data from a drug monitoring system used by the Department of Rheumatology at the Haywood Hospital to identify patients likely to require a change in their medication based on their blood results.
114

Cocaine metabolism in Pseudomonas maltophilia MB11L

Britt, Adrian John January 1991 (has links)
No description available.
115

Cyclooxygenase 2 inflammation

Gilroy, Derek William January 1997 (has links)
No description available.
116

Synthesis of the anthraquinone portion of dynemicin A : Taxanes chiral construction of the A, B and C rings of taxol

Magnus, Nicholas Andrew January 1996 (has links)
No description available.
117

The lethal and non-lethal effects of ivermectin on cattle dung on the fly Neomyia cornicina

Gover, Jane Charlotte January 1995 (has links)
No description available.
118

Variation in prescribing in general practice

Carthy, Patricia Ann January 2000 (has links)
No description available.
119

The actions of centrally acting muscle relaxants on synpatic reflexes of motoneurones in vitro

Siarey, Richard John January 1992 (has links)
No description available.
120

Development of enzyme assays for heroin and morphine

Holt, Peter-John January 1995 (has links)
No description available.

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