Global ETD Search

211	Disease modeling of pulmonary fibrosis using human pluripotent stem cell-derived alveolar organoids / ヒト多能性幹細胞由来の肺胞オルガノイドを用いた肺線維症の疾患モデリング Suezawa, Takahiro 26 September 2022 (has links) 京都大学 / 新制・論文博士 / 博士(医学) / 乙第13502号 / 論医博第2261号 / 新制\|\|医\|\|1061(附属図書館) / (主査)教授村川泰裕, 教授柳田素子, 教授長船健二 / 学位規則第4条第2項該当 / Doctor of Medical Science / Kyoto University / DFAM pluripotent stem cells pulmonary fibrosis epithelial-mesenchymal interaction ALK5 integrin αVβ6 490
212	Structural Investigation of the Complex of Filamin A Repeat 21 with Integrin αIIb and β3 Cytoplasmic Tails – A Potential “Transmission” to Regulate Cell Migration Liu, Jianmin January 2009 (has links) No description available. Analytical Chemistry Biochemistry Biomedical Research Biophysics Chemistry Structural biology NMR integrin filamin cell migration
213	Leukocytes and inflammation in the pathogenesis of the early stages of diabetic retinopathy Veenstra, Alexander A. January 2013 (has links) No description available. Pharmacology Molecular Biology leukocytes diabetic retinopathy retina inflammation neutrophil inhibitory factor NFkB1 integrin amb2
214	RAP1-TRIGGERED PATHWAYS FOR TALIN-MEDIATED INTEGRIN ACTIVATION Zhu, Liang 01 February 2018 (has links) No description available. Biochemistry Cellular Biology Molecular Biology Biophysics
215	Studies of Protein S-nitrosylation in Prostate Cancer focused on Integrin Alpha 6, Proliferating Cell Nuclear Antigen and Estrogen Receptor Beta Isaac, Jared 16 October 2012 (has links) No description available. Surgery Prostate cancer S-nitrosylation Integrin alpha 6 PCNA ER beta Cell migration
216	Ultraviolet B-induced and Nitric Oxide-mediated Cellular Signaling Circuit and Its Physiological Impacts Wang, Lei 23 September 2010 (has links) No description available. Biochemistry Biology Biomedical Research Cellular Biology nitric oxide ultraviolet B zinc melanoma metastasis VLA-4 integrin
217	Integrin-mediated alterations in chromatin and DNA repair proteins Rose, Jane Lande 09 March 2005 (has links) No description available. Health Sciences, Pharmacy ¿¿¿¿g DNA BLM MLEC histone PARP-1 integrin
218	Targeting the phosphoinositide-dependent protein kinase-2 for anticancer drug discovery Lee, Su-Lin 25 June 2012 (has links) No description available. Cellular Biology Chemistry Organic Chemistry Pharmacology Drug discovery inhibitor integrin-linked kinase PDK2
219	Effect of Macrophage Expressed α7 Nicotinic Acetylcholine Receptor (α7nAChR) on Migration of Macrophages During Inflammation Keever, Kasey 01 December 2023 (has links) (PDF) Sepsis is a life-threatening condition characterized by overwhelming inflammation, resulting in organ system damage, leading to a high mortality rate. Care in the clinical setting is supportive, and there are no approved sepsis-specific treatments. In septic mice, activation of the cholinergic anti-inflammatory pathway decreases cytokine secretion by leukocytes and improves survival. The cholinergic anti-inflammatory pathway is a reflex of the parasympathetic nervous system, converging on the α7 nicotinic acetylcholine (α7nAChR) at the surface of macrophages. Signaling through the receptor blocks NF-kB activation, thus cytokine secretion. Receptor activation has other effects on macrophages, including modulating their migration to target tissues during inflammation. The goal of this study was to describe the contribution of α7nAChR to macrophage migration during sepsis, using both activation with agonist PNU-282987 and α7nAChR-/- mice. We showed that α7nAChR-deficiency impedes migration to inflamed tissues, and that α7nAChR activation promotes macrophage accumulation in tissues, an effect mediated through altered expression of integrin aMb2. α7nAChR macrophages sepsis integrin αMB2 migration Biology Immunity Immunology and Infectious Disease
220	Effect of transforming growth factor-β on up/down regulation of integrin-β1 in primary chondrocyte culture Khaghani, Seyed A., Sefat, Farshid, Youseffi, Mansour, Rehman, R., Soon, Chin Fhong, Akbarova, G. January 2016 (has links) yes / Regeneration of a damaged or non-functioning tissue requires adhesion of cells to their extracellular matrix (ECM). Thus the investigation of the level of synthesised cell adhesion molecules (CAMs) in cell culture systems play major roles in cell and tissue engineering. Adhesion of chondrocyte to a collagen type-II rich matrix, is dependent on cell adhesion molecules (CAMs) and integrins and cells adhere to ECM through integrins.

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