No description available.

No description available.

Antibodies specific for insulin and human immunoglobulin G (HlgG) were attached to controlled pore glass (CPG) particles which had been silanized with a diol-bearing silane. Up to 20 mg of antibody protein could be attached covalently to 1 gram of CPG. Such immobilized antibodies, or immunosorbents, would bind specific antigens, but not unrelated proteins, when used in a high pressure liquid chromatographic configuration. This technique was given the name "high performance immunoaffinity chromatography" (HPIC). The HPIC properties of these immunosorbents were evaluated by an equilibrium theory and were found to be comparable to batch values. An immunosorbent for HIgG antigen showed an HPIC association constant of 10⁷·⁶; the batch equilibrium constant for the same immunosorbent was 10⁷·⁸. Two different anti-insulin immunosorbents retained the intrinsic affinity (10⁶ and 10⁹) of the antibody used to make them. The total active antibody concentrations of these immunosorbents were evaluated by HPIC and batch methods with good agreement between the two. The immobilization reaction was seen to result typically in the loss of 90% of the original antibody activity. HPIC was shown to be applicable to the rapid analysis of antigens at levels as low as ng/mL. This was found to be possible in part because of the rapid forward kinetics which were assessed by HPIC. A forward rate constant of 3 X 10⁷ L·mol⁻¹·sec⁻¹ for the binding of insulin by a specific HPIC column could be determined. The possibility of HPIC fluorescence immunoassays was investigated using a highly sensitive fluorescence detector. An Eimac collimated xenon arc lamp provided sufficient power to detect picomolar levels of fluorescamine labeled insulin and other compounds. The limitations of HPIC in performing picomolar immunoassays were thus shown to be immunochemical rather than instrumental. The ability of immunoaffinity purifications to overcome these limitations was demonstrated.

No description available.

Magister Scientiae Dentium - MSc(Dent) / The Tip-Edge and edgewise techniques are the main techniques that are mostly used in orthodontics, and are applicable to the treatment of any type of malocclusion from the most simple to the most complex. The edgewise bracket wire combination produces bodily tooth movement simultaneously or separately in all three planes of space and hence permits correction of the most extreme tooth malpositions. On the other hand Tip-Edge offers a differential tooth movement (just like the previously used Begg technique) within an edgewise based bracket system (Parkhouse 2003). When treating patients using the Tip-Edge technique, it is recommended that a specialized archwire i.e. Australian stainless steel wire be used. This wire can be described as a round austenitic stainless steel wire that is heat-treated and cold-drawn to its proper diameter. This was done in order to produce its special and needed properties such as toughness, resiliency and tensile strength (Kesling, 1985). It is used in conjunction with light (2oz) class II elastics. The aim of this study was to compare cephalometric changes in skeletal and dento-alveolar parameters in cases treated by these two different orthodontic techniques. This was to be established by calculating and comparing the pre- and post-treatment cephalometric variables of cases treated with these techniques by looking at the skeletal and dento-alveolar measurements. Thirty Tip-Edge and thirty edgewise treated cases that had class II malocclusion, had extraction of four premolars and were treated with Class II elastics were selected. The gender distribution between the Tip-Edge and the edgewise techniques were 47% and 60% respectively for females. For males it was 53% in Tip-Edge and 40% in the edgewise techniques.

This thesis explores Lucien Capet's bowing technique and identifies connections to contemporary violin bowing practices. It includes a developed biography of Capet; a review of the Capet treatise; a historical analysis linking Capet's bowing technique back to his predecessor Baillot and forward to the present day; a detailed comparative analysis that determines Capet's pedagogical connections to Ivan Galamian and Simon Fischer; and an examination of the ramifications of the results including the the finding that Capet's technique is a viable and important component to developing refined contemporary bowing technique.

Since the Software Engineering Institute published the Capability Maturity Method Integration (CMMI) in 2003, many software firms have implemented it to enhance its software quality assurance and international collaboration. Analysis and design phases are two important phases for the software development. The artifacts of these two phases mainly represented using the structured technique or the object-oriented technique. This study proposed a methodology which provides guidelines to compare the artifacts of these two techniques for an embedded system. The research methodology is articulated using the design science research methodology. A usability valuation with a real-world embedded system case is performed to demonstrate its applicability. The results provide evidences to enhance our understanding about the strength and weakness of these two nalysis and design techniques.

Chemical vapor deposition is an important thin film process for the fabrication of TFT-LCD(Thin-Film-Transistor Liquid Crystal Display), the heat transfer coefficient on the substrate is the important influence parameter in the manufacturing process. For this reason, the main object of this thesis is to set up a temperature measurement system of transient thermochromatic liquid crystals. Furthermore, an experimental is carried out in the present study to investigate the characteristics of heat transfer resulting from a low speed air jet impinging onto a rectangular substrate confined in a vertical rectangular chamber. Finally, empirical equations are proposed to correlate the effect of Reynolds number¡BSeparation distances and Ratio of outlet.

Diss.--Mannheim, 1998.

Reproduction de : Thèse de doctorat : Génie des procédés et systèmes industriels : Toulouse, INPT : 2006. / Titre provenant de l'écran titre. Bibliogr. 217 réf.