The purpose of this work was to determine the possible effects of isolated spinal ligament transection on the biomechanics of the lumbar spine. A finite element model of a lumbar spine was developed and validated against experimental data. The model was tested in the primary modes of spinal motion in the intact condition, followed by comparative analysis of isolated removal of each spinal ligament. Results showed that stress increased in the remaining ligaments once a ligament was removed, potentially leading to ligament damage. Results also showed changes in bone remodeling "stimulus" which could lead to changes in bone density. Isolated ligament transection had little effect on intervertebral disc pressures. All major biomechanical changes occurred at the same spinal level as the transected ligament, with minor changes at adjacent levels. The results of this work demonstrate that iatrogenic damage of spinal ligaments disturbs the load sharing within spinal-ligament complex and may induce significant clinical changes in the spinal motion segment.

The purpose of this research was to investigate the influence of applying an intrinsic decompressive pre-load to a particular dynamic stabilization device on the biomechanical response of the lumbar spine. The FlexSPAR, which supports this ability, was used as a test case. A finite element model of a full lumbar spine was developed and validated against experimental data, and tested in the primary modes of spinal motion. The model was used to compare five lumbar spine test cases: healthy, degenerate, implanted with a pre-loaded device, implanted with a device without a pre-load, and implanted with rigid fixators. Results indicated that a pre-loaded FlexSPAR led to improved disc height restoration and segmental biomechanics. Results also showed that a pre-loaded FlexSPAR led to less change in bone remodeling stimulus in comparison to the device without a pre-load and rigid fixators. This work shows that there is a potential to improve the performance of posterior dynamic stabilization devices by incorporating a pre-load in the device.

The purpose of this research was to design, develop, and test coronary stent designs composed of carbon-infiltrated carbon nanotubes (CI-CNTs). Coronary stents currently have two major complications: restenosis and thrombosis. CI-CNT stents have potential to address both of these issues, and therefore may provide improved clinical outcomes. CI-CNT stent geometry is patterned using high-resolution photolithography that provide advantages in design possibilities.To develop a coronary stent, a standard design process was followed including: background, design specifications, concept generation, development, analysis, and testing. Background research was first completed and general design specifications for coronary stent performance were compiled. Multiple design concepts were generated, evaluated, and finally a design was selected. This stent design was further developed and optimized using analytical tools along with finite element analysis. This stent design used tapered struts in repeating segments to reduce stress and improve radial force. The design was modeled and analyzed as both a flat geometry as well as in a cylindrical configuration. Mechanics of materials equations and geometry specific finite element analysis were used to guide the final coronary stent design. The stent design was tested mechanically, and additional tests were performed to verify the blood compatibility of the CI-CNT material. The flat version of the stent design was manufactured and mechanically tested to verify performance. The performance of the cylindrical stent configuration was analyzed using an FE model of an atherosclerotic artery. This arterial FE model was created and validated by analyzing balloon angioplasty of a common stainless steel stent. The biocompatibility of CI-CNTs was explored and studied. Blood compatibility testing of CI-CNT samples was performed with results comparable in performance to stainless steel. A method of stent deployment was planned, and several other stent design concepts were analyzed. This research demonstrates that a functioning coronary stent can be manufactured from CI-CNTs. The optimized design has potential to address problems currently associated with stents. However, a major challenge for CI-CNT stent designs is meeting the design requirement of sufficient radial force. CI-CNT stents also need to have excellent blood compatibility to justify being used in stent applications.

With the desire for conventional coal-fired power plants to perform flexible operations, the impact of this operation has become important to the field of steam turbine modelling. This study sought to develop a computationally inexpensive turbine model with minimal OEM intervention in order to predict the internal clearances of high-pressure and intermediate-pressure turbines from Eskom's current turbine fleet. The study saw the utilisation of the Nozzle Analogy theory to develop a 1D multistage turbine thermofluid model as well as the development of a representative 1D turbine process model in order to predict the internal temperature gradients promoted within a steam turbine during transient operation. From this model a further 3D FEA turbine model of both the HP and IP turbine units were developed from simple turbine diagrams to apply the predicted temperature boundaries and predict the thermal and structural response of turbine components during transient loading during a full Cold Start procedure. The result of this study was the successful validation of the 1D and 3D Turbine models against plant data from the candidate unit. This was in the form of known process data of unit performance, as well as thermocouple and differential expansion data taken from sensors housed on the turbine unit itself. Through the validation of these parameters, various calibrations techniques were developed over the course of the study with these techniques allowing investigators to gain insight into turbine aging, operator intervention as well as brought turbine component response. The successful establishment of the paired turbine model allowed investigators to evaluate the cold clearances defined during construction and maintenance of these turbine units in industry, which contributes greatly to the availability and efficiency of the unit during these transient operations. Additionally, the establishment of this model allowed for the investigation of the role that start up speed has on turbine component response. This study demonstrated that the development of such a modelling methodology was possible and yielded results with were accurate and insightful in understanding turbine component responses which are otherwise impossible to measure during real-world operation.

In collaboration with Kongsberg Automotive, the thesis focuses on material selection and redesigning the shift fork for additive manufacturing using topology optimization. The shift fork is a component in the gear shifting mechanism in the automotive industry. The current shift fork at Kongsberg is manufactured from aluminum using die-casting. This design and material do not withstand huge dynamic loads in commercial vehicles. The material to withstand the loading conditions and is widely available across powder manufacturers is selected using the weighted properties method. The topology optimization of the design resulted in a 50 % reduction in mass. The shift fork's two legs undergo uneven load distribution due to eccentricity. The optimized models are simulated using Finite Element Analysis to validate the design. The optimized design is obtained such that the difference in displacement between both legs is within 50 %. Numerous metal powder manufacturers and 3D printing service providers were contacted to understand the current additive manufacturing market.

No description available.

Compared to traditional thermal spray, cold spray as a new emerging surface treatment eliminates or substantially reduces phase transformation of deposited material and reduces coating porosity. Therefore, the appearance of this new type of surface treatment and additive manufacturing process has attracted considerable attention from researchers. In this research, three-dimensional modeling of Al6061-T6 particle impact and cohesion process was simulated by utilizing commercial finite element analysis (FEA) software ABAQUS/Explicit. To guarantee that a stable bonding phenomenon can be realized in the scope of physical validity, a built-in cohesive contact behavior model was implemented in the simulation to understand the bonding phenomenon. A non-planar surface was introduced to replace the usual planar impacted surface to mimic micron-scale curvature of the sprayed target in the real condition. Simulation models of spraying particles impact on positions with spray angle corresponding to 90°, 80°, 70° were created to investigate the effect generated by the curvature for the residual stress after bonding. Curvature function was exploited to describe the non-planar surface wavy condition derived from optimized impacting angle for achieving bonding phenomenon. This numerical simulation work can provide further insights for the residual stress evolution status in the condition of realized cohesion between impactor and non-planar surface after a kinetic peening process. Beneficial suggestions toward cold spray technology utilization in additive manufacturing areas are concluded from the results of the numerical simulation.

Femoroacetabular impingement (FAI) is recognized as a pathomechanical process that leads to hip osteoarthritis (OA). It is hypothesized that mechanical stimuli are prominent at higher range of motions in hips with cam FAI (aspherical femoral head-neck deformity). Adverse loading conditions can impose elevated mechanical stimuli levels at the articulating surfaces and underlying subchondral bone, which plays a predominant mechanical role in early OA. The aim of this research was to determine the levels of mechanical stimuli within the hip, examining the effects of severe cam impingement on the onset of OA, using patient-specific biomechanics data, CT data, and finite element analysis (FEA). Patient-specific hip joint reaction forces were applied to two symptomatic patient models and two control-matched models, segmented from patient-specific CT data. The finite element models were simulated to compare the locations and magnitudes of mechanical stimuli during two quasi-static positions from standing to squatting. Maximum-shear stress (MSS) was analyzed to determine the adverse loading conditions within the joint and strain energy density (SED) was determined to examine its effect on the initiation of bone remodelling. The results revealed that peak mechanical stimuli concentrations were found on the antero-superior acetabulum during the squatting position, underlying to the cartilage. The MSS magnitudes were significantly higher and concentrated for the FAI patients (15.145 ± 1.715 MPa) in comparison with the MSS magnitudes for the control subjects (4.445 ± 0.085 MPa). The FAI group demonstrated a slight increase in peak SED values on the acetabulum from standing (1.005 ± 0.076 kPa) to squatting (1.018 ± 0.082 kPa). Insignificant changes in SED values were noticed for the control subjects. Squatting orients the femoral head into the antero-superior acetabulum, increasing the contact area with the cartilage and labral regions, thus resulting in higher peaks behind the cartilage on the acetabulum. The resultant location of the peak MSS and SED concentrations correspond well with the region of initial cartilage degradation and early OA observed during open surgical dislocation. Due to the relatively low elastic modulus of the articular cartilage, loads are transferred and amplified to the subchondral bone. This further suggests that elevated stimuli levels can provoke stiffening of the underlying subchondral plate, through bone remodelling, and consequently accelerating the onset of cartilage degradation. Since mechanical stimuli results are unique to their patient-specific loading parameters and conditions, it would be difficult to determine a patient-specific threshold to provoke bone remodeling at this stage.

In this thesis an investigation of the shear stiffness and capacity of joints between pre- fabricated concrete elements regarding to different material properties is reported. Two different models of shear key joints, connected to prefabricated walls, were cre- ated in the non-linear finite element software, ATENA 3D, with the aim to estimate a realistic behaviour of the joints regarding to the external loads.

Car collisions are, unfortunately, not uncommon and cause 1.35 million deaths each year worldwide. Children are often occupants in cars and to ensure their safety, child restraint systems (CRSs) have been developed. However, CRSs need to be used correctly to be efficient. Several studies, such as field investigations and Q-dummy tests, have shown that a misuse of a CRS can increase the risk of injuries. Typical misuses for a forward-facing CRS and a booster seat, with two real accident parameters, were constructed and simulated using the PIPER child human body model. The kinematics of each case were compared with injury parameters of the head, neck and abdomen. Comparing the parameters to existing injury criteria showed that most of the cases end in AIS3+ head injury, even cases with no misuse. When comparing the results of misuses to the cases where the CRS was correctly used, the dominant result was that misuse resulted in being less effective to protect the child. Moreover, results of chosen misuses compared to Q-dummy tests correlated with their results. Results from this thesis illustrate how important it is for parents to restrain children and route the belt correctly.