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This thesis is missing page 155, the other copies of the thesis are also missing this page. -Digitization Centre / This thesis develops a two dimensional Viterbi Algorithm for the maximum likelihood sequence estimation over band limited baseband channels with intersymbol interference. Degradation, decision depth, 99% energy bandwidth and the channel cost are used as the performance measures for the comparisons of different channels. The four measures are extensively evaluated for channels with length up to four signalling intervals. The results of each measure are presented in contour form. Error events analysis shows that the degradation contours are governed by elliptical equations. Maximum degradation results from state path merge at a depth equal to the channel length plus one. By analysing periodic state sequences, we found that catastrophic error propagation contours are mainly governed by linear equations. Generally, channels with longer length have narrower minimum bandwidth but higher degradation. A channel cost similar to Shannon capacity equation is proposed to jointly minimize both degradation suffered and bandwidth required for signalling over a channel. According to the equation, the channel cost is influenced more by the bandwidth than by the degradation and thus the regions of low channel cost lie on the regions of narrow bandwidth. Also low channel cost regions are found to be on the regions of long decision depth and thus require higher complexity for maximum likelihood sequence estimation. In addition, it is found that minimum channel cost decreases with increasing channel length. / Thesis / Master of Engineering (ME)

This thesis presents a study of the effectiveness of a blocked series of stimulus presentations in training pigeons to perform a discrimination. It was found that this sequence of trial presentations was a least as effective as training with a random sequence of trial presentations. / Thesis / Master of Arts (MA)

As you move among the various spaces within the school you will notice that the volume is an encapsulation made from surfaces that describe what is material and what is void of material. This makes for interaction of the senses. What can be formed in material can transcend from built form directly and indirectly to the student through the duration of observation. Thus augmenting their knowledge and judgement. What can not be formed from material has to be thought of in a different way for the student.This nonmaterial form is subject to what binds it, making the experience from nontactile things such as light and darkness. The thesis undertook these conditions to make a place where observation is inclusive. Observation is the step in which a student must invoke their intellect to understand their purpose as an artist and to define their own uniqueness. Perhaps this is an atypical way for students to learn with regard to art but the making of art should be anything but typical. / Master of Architecture

Among all existing alignment-free methods for comparing biological sequences, the sequence graphical representation provides a simple approach to view, sort, and compare gene structures. The aim of graphical representation is to display DNA or protein sequences graphically so that we can easily find out visually how similar or how different they are. Of course, only the visual comparison of sequences is not enough for the follow-up research work. We need more accurate comparison. This leads us to develop the application of the graphical representation for biological sequences. / In this thesis, we have two main contributions: (1) We construct a protein map with the help of our proposed new graphical representation for protein sequences. Each protein sequence can be represented as a point in this map, and cluster analysis of proteins can be performed for comparison between the points. This protein map can be used to mathematically specify the similarity of two proteins and predict properties of an unknown protein based on its amino acid sequence. (2) We construct a novel genome space with biological geometry, which is a subspace in RN . In this space each point corresponds to a genome. The natural distance between two points in the genome space reflects the biological distance between these two genomes. Our genome space will provide a new powerful tool for analyzing the classification of genomes and their phylogenetic relationships. / Yu, Chenglong. / Adviser: Luk Hing Sun. / Source: Dissertation Abstracts International, Volume: 72-04, Section: B, page: . / Thesis (Ph.D.)--Chinese University of Hong Kong, 2010. / Includes bibliographical references (leaves 59-64). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. Ann Arbor, MI : ProQuest Information and Learning Company, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. Ann Arbor, MI : ProQuest Information and Learning Company, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstract also in Chinese.

International Telemetering Conference Proceedings / October 26-29, 1998 / Town & Country Resort Hotel and Convention Center, San Diego, California / This paper analyzes the pseudo-random characteristic of m-sequence and proposes a spread spectrum communication scheme in which the phase-shifting sequences of msequence can be used as the spread spectrum code under given condition. Therefore, the available spread spectrum code set is expanded. It is theoretically proved that there are some advantages in using phase-shifting sequences instead of the conventional msequences or GOLD-sequences in spread spectrum communication system.

The topic of the diploma work is the use of modern methods in the management of stock. Stock represents very important part of the company's economy; its right level contributes to the increase of competitiveness of the company. The diploma work states the theoretical basis for management of stock and analyzes in detail the chosen methods -- kanban a Just-In-Sequence, which is often understood as a next step in implementation of the pull principle -- consumption manager inventory. The main aim of the work is the analysis of definition of the stock for the system of kanban and Just-In-Sequence and definition which effect have it's parts on the stock. According to a target of the work a hypothesis was defined. The right implementation of kanban, or Just-In-Sequence and incidence on it's parts contributes to a reduction of stock. The practical part of the work analyzes in detail the formulas of calculation of the stock in the system of kanban, it's factors are simulated and the level of stock examined. Accordingly, the comparison of the system of kanban and Just-In-Sequence is provided. In the end of the work the recommendations for implementation of kanban and Just-In-Sequence are made. Also the successfulness of the implementation of new methods in the defined company is evaluated and recommendations are prepared.

L’un des enjeux de la lutte contre le cancer réside dans la compréhension de l’hétérogénéité de la maladie. Le but de notre travail a été d’explorer l’hétérogénéité des cellules cancéreuses du point de vue de la séquence d’ARN messager. Les ESTs (ou Expressed Sequence Tags) d’origine humaine ont été alignées aux séquences de référence ARNm. Les alignements ont été exploités de manière à mesurer les variations de séquence des ESTs issues de tissus tumoraux ou non tumoraux à chaque position de chaque transcrit. L’analyse statistique mise en place a consisté à identifier les positions pour lesquelles les variations de séquence, i.e. substitutions, insertions et délétions, sont différentes entre les ESTs d’origine tumorale et les ESTs d’origine non tumorale. L’étude bioinformatique s’est d’abord concentrée sur 17 transcrits abondamment exprimés avant d’être étendue à l’ensemble du transcriptome. Elle a ensuite été réalisée sur les ESTs murines. Les résultats montrent que l’hétérogénéité des transcrits cancéreux est plus grande que celle des tissus sains. Ainsi, l’infidélité de transcription est augmentée au cours de la carcinogénèse. Ce résultat bioinformatique a été validé par différentes approches biologiques. Tout d’abord, le clonage puis le séquençage d’un ARN provenant d’une tumeur pulmonaire humaine et présentant une délétion prédite de manière bioinformatique ont été réalisés, et ce, en l’absence de mutation somatique. Ensuite, l’identification par spectrométrie de masse d’un variant protéique issu de la traduction d’un ARN dont le codon stop est substitué en triplet codant a été possible. Enfin, l’intérêt de rechercher dans le sérum de patients cancéreux la présence d’anticorps dirigés contre des protéines issues de la traduction d’ARNm infidèles a été démontré. Ainsi, l’infidélité de transcription est un phénomène augmenté dans le cancer et responsable d’une partie de l’hétérogénéité des cellules cancéreuses. L’intérêt de cette découverte réside dans les perspectives nouvelles qu’elle offre en termes de compréhension des mécanismes de carcinogénèse et en termes de diagnostic de la maladie / One of the aim of the fight against cancer is to understand the heterogeneity of cancer cells. The goal of our work has been to explore cancer cell mRNA heterogeneity. ESTs (Expressed Sequence Tags) extracted from normal and cancer tissues have been aligned to mRNA reference sequences. This allowed identification of non-random sequence variations that occurred at statistically significant increased rates in cancer compared to normal libraries. This analysis first focused on 17 abundant transcripts and was next extended to whole human genome, as well as to that of Mus musculus. The results show an increase of transcription infidelity events in cancer tissues. Three types of events occur, i.e. base substitutions, deletions and insertions. Bioinformatics results have been validated through different biological methods. First, the cloning and sequencing of mRNA from lung cancer human with a deletion occurring at bioinformatically predicted position in absence of somatic mutation has been achieved. Then, mass spectrometry analysis confirmed the existence of protein variants resulting from translation of mRNA bypassing stop codon. Finally, we showed that transcription infidelity peptides contain specific epitopes of immunoglobulins ; detection of changes in immunoglobulins in patients with cancers opens a novel path toward early stage cancer diagnosis. This increased transcription infidelity in cancer contributes to the heterogeneity of cancer cells. This finding opens novel perspectives and strategies toward understanding carcinogenesis and diagnostic of the disease

Hu, Xihao. / Thesis Ph.D. Chinese University of Hong Kong 2015. / Includes bibliographical references (leaves 147-161). / Abstracts also in Chinese. / Title from PDF title page (viewed on 26, October, 2016). / Hu, Xihao.