Bibliography: p. 189-229. / xiii, 230 p., [4] leaves of plates : ill. ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis (Ph.D.)--University of Adelaide, Dept. of Public Health, 2002

"16th September 2002." / Accompanying CD contains 2 MPEG clips with accompanying text, and a copy in PDF format of: Recovery of airway cystic fibrosis transmembrane conductance regulator function in mice with cystic fibrosis after single-dose lentivirus-mediated gene transfer / M. Limberis ... [et al.], published in Human gene therapy vol. 13 (2002). / Bibliography: leaves xxix-li. / xxvii, 213, li leaves : ill., plates (some col.) ; 30 cm. + 1 CD-ROM (4 3/4 in.) / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / This thesis focuses on modulating the physical barriers of the airway epithelium with mild detergents, so as to enhance gene transfer by a HIV-1 based lentivirus vector in vivo. The efficiency of the gene transfer was evaluated in the nasal airway of C57B1/6 mice using the Lac Z marker gene. This demonstration of lentivirus-mediated in vivo recovery of CFTR function in CF airway epithelium illustrated the potential of combining a pre-conditioning of the airway surface with a simple and brief HIV-1 based gene transfer vector exposure to produce therapeutic gene expression in the intact airway. / Thesis (Ph.D.)--University of Adelaide, Dept. of Paediatrics, 2003

Zugl.: Göttingen, Univ., Diss., 2005

No description available.

<p>The doctoral thesis sets out to describe and analyse how the mid-twentieth century Norwegian design community domesticated ideologies partly inherited from the traditional applied art movement (brukskunstbevegelsen), partly imported from various international currents of the so-called “modern movement”, in their co-construction of industrial design culture. The empirical studies follow two paths/levels; the ideology/propaganda debated in and mediated through the design magazine Bonytt, and the strategies/materiality/products developed by the ceramics/earthenware/porcelain manufacturer Figgjo. As such, the thesis is a cultural history of industrial design, where design (as) culture is seen as a sort of dialectic or discourse between ideology and practice. This often uneasy relation between ideology and practice is the leitmotif of the study. The concept of domestication, along with other theoretical frameworks and methodological tools appropriated from STS, becomes valuable when studying this process by following the actors in their construction, negotiation and mediation of these ideologies as played out in their main debate forum, the design magazine Bonytt. However, the domestication of industrial design culture in Norway does not end with the writings of campaigning designers, enthusiastic journalists, ardent academics and organization men. The mediations between ideology and practice is also traced in a domestication perspective. As such, the manufacturing industry - here represented by the ceramic tableware manufacturer Figgjo - represents a second site of domestication, where the ideologies undergo new negotiations and transformations in meeting other users, requirements and circumstances.</p>

La précipitation de phases durcissantes dans les alliages métalliques est une préoccupation industrielle et scientifique majeure. En effet, l’'ajout de quelques éléments d’'alliages, même en faible quantité, peut changer radicalement les propriétés d’'usage de bon nombre de matériaux métalliques. Or, les premiers instants de la précipitation sont, à l’'heure actuelle, mal connus. Quels sont les paramètres qui régissent la morphologie des précipités ? Pourquoi certains précipités germent-ils sur les dislocations ? Pourquoi la chimie des précipités est-elle parfois différente de celle du même matériau massif ? L’'ambition de ce mémoire n’'est pas de trouver des réponses à toutes ces questions, mais de proposer une approche qui combine les outils expérimentaux locaux (microscopies) et globaux (pouvoir thermo- électrique, diffusion des rayons X,..) à des techniques de modélisation allant de l’'échelle atomique (dynamique moléculaire, Monte-Carlo cinétique) à l’'échelle mésoscopique (théorie « classique » de la germination, thermodynamique). Dans ce mémoire, un point est fait sur les travaux que j’'ai réalisés dans ce domaine au laboratoire MATEIS et sur les collaborations qu’'ils ont impliquées. Une large place est faite aux perspectives dégagées par ces quelques années de recherche et d’'enseignement effectuées à l’'INSA de Lyon.

<p>Correct certificate revocation practices are essential to each public-key infrastructure. While there exist a number of protocols to achieve revocation in PKI systems, there has been very little work on the theory behind it: Which different types of revocation can be identified? What is the intended effect of a specific revocation type to the knowledge base of each entity?</p><p>As a first step towards a methodology for the development of reliable models, we present a graph-based formalism for specification and reasoning about the distribution and revocation of public keys and certificates. The model is an abstract generalization of existing PKIs and distributed in nature; each entity can issue certificates for public keys that they have confidence in, and distribute or revoke these to and from other entities.</p><p>Each entity has its own public-key base and can derive new knowledge by combining this knowledge with certificates signed with known keys. Each statement that is deduced or quoted within the system derives its support from original knowledge formed outside the system. When such original knowledge is removed, all statements that depended upon it are removed as well. Cyclic support is avoided through the use of support sets.</p><p>We define different revocation reasons and show how they can be modelled as specific actions. Revocation by removal, by inactivation, and by negation are all included. By policy, negative statements are the strongest, and positive are the weakest. Collisions are avoided by removing the weaker statement and, when necessary, its support.</p><p>Graph transformation rules are the chosen formalism. Rules are either interactive changes that can be applied by entities, or automatically applied deductions that keep the system sound and complete after the application of an interactive rule.</p><p>We show that the proposed model is sound and complete with respect to our definition of a valid state.</p> / Report code: LIU-TEK-LIC-2006:1

<p>Due to the globalization trend, the transformation of Chinese OEM has become a hot topic in the last decades. Although the previous literature suggested that there were many different determinants influencing firms to be successful companies, there is a lack of combination in the context of Chinese OEM. Thus, the purpose of this research study is to find out the approach of Chinese OEMs to successfully launch their own products based on three perspectives - organizational structure, processes and culture.Applying a qualitative approach, the data was gathered through semi-structured telephone interviews with the senior personnel of one Chinese OEM company (Damekiss), complemented with secondary data collected from the company’s and public websites.The results of analysis showed different views of how organizational structure, process and culture influencing on the transformation of Chinese OEM. We found that four functions (i.e. manufacturing, distribution, new product development and human resource management) influenced the transformation of Chinese OEM in organizational structure perspective. Among these functions, human resource management and distribution are extremely weak in the organizational structure of Chinese OEM. Regarding to the process of formulating these functions, the deep understanding of the customers’ preferences and collaboration partners that influenced building distribution were figured out. In the case company, it showed a relative poor ability on distribution which would be the barriers for further developing. Building HRM process was raised as another issue of the transformation of Chinese OEMs. According to the case company, HRM was poorly organized. The recruitment did not get enough attention; the training programs stayed at a lower level. The last not least, the corporate culture was also proven to be playing an important role in the transformation of Chinese OEMs. Awareness of corporate culture as one of significant aspects influencing the entire company was found in the case company. Slogan, company heroes and rituals as an internal culture were properly used to motivate employees.</p>

<p>In this project I have tried to obtain stable transformants of <em>Drosophila</em> melanogaster flies using electroporation. I have completed approximately 200 tests using different DNA concentrations, voltages and cuvettes, including a novel Petri dish cuvette which I developed and manufactured myself. I also developed new and more efficient procedures of egg collection and egg dechorionation. Although I was not  successful in obtaining true stable transformants, control experiments indicate that electroporation of DNA into embryos could be accomplished under the conditions used. The lack of stable transformants was probably due to failure of the electroporated DNA to integrate into the host genome. The reasons for why the DNA did not integrate was not further investigated in this study.</p>

TiNi films were prepared by co-sputtering TiNi target and a separate Ti target. Crystalline structure and phase transformation behaviors of TiNi films were investigated. Results showed that TiNi films had fine grain size of about 500 nm and fully martensitic structure at room temperature. X-ray photoelectron spectroscopy (XPS) results indicated that there is adherent and natural TiO₂ film, which is beneficial to its corrosion resistance and biocompatibillity. Results from differential scanning calorimeter (DSC), in-situ X-ray diffraction (XRD) and curvature measurement revealed clearly martensitic transformation upon heating and cooling. The TiNi films were further deposited on micromachined silicon cantilever and membrane structures in order to form micro-gripper or microvalve with large deformation due to shape-memory effect. / Singapore-MIT Alliance (SMA)